research Retinoic acid exerts sexually dimorphic effects on muscle energy metabolism and function
Retinoic acid affects male and female muscle energy use and function differently.
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research Probing androgen receptor co-factor selectivity profiles: a chemical tool to determine cross-talk between androgen receptor and β-catenin in vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research The association of cytosine-adenine-guanine repeat polymorphism in the androgen receptor gene with nodulocystic acne in Egyptian patients
Certain gene variations are linked to severe acne in Egyptian patients and could guide treatment choices.
research 任意方向の負荷に対する多自由度機構の出力変位誤差評価 : 評価法の提案と3自由度空間パラレルメカニズムの高剛性化(機械力学,計測,自動制御)
Minoxidil sulfate and pinacidil promote hair growth likely by increasing blood flow, not by activating K channels.
research Joint study of the associations of HLA‐B and the transmembrane short tandem repeat polymorphism of MICA protein with alopecia areata shows independent associations of both with the disease
Both HLA-B and MICA are independently linked to alopecia areata.
research Acute sensitivity of the oral mucosa to oncogenic K‐ras
Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.
research Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole‐body energy expenditure
Alkaline ceramidase 1 is crucial for healthy skin and energy balance.
research MULTIPLE HEMANGIOMAS OF THE TONGUE AND ORAL CAVITY IN A MYOTONIC DYSTROPHY TYPE 1 PATIENT: A CASE REPORT
A patient with Myotonic dystrophy type 1 had multiple tongue hemangiomas and was sensitive to anesthesia.
research Localization of sex steroid receptors in human skin.
Sex steroid receptors are found in specific skin cells, affecting skin and hair functions.
research Different Ligands of the TRPV3 Cation Channel Cause Distinct Conformational Changes as Revealed by Intrinsic Tryptophan Fluorescence Quenching
Different ligands change the shape of the TRPV3 ion channel in unique ways.
research Faculty Opinions recommendation of Identification of drug-specific public TCR driving severe cutaneous adverse reactions.
Researchers found a specific T cell receptor linked to severe drug reactions like Stevens-Johnson syndrome when patients take carbamazepine.
research Genetically modified laboratory mice with sebaceous glands abnormalities
Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
research The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating
5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.
research New fluorogenic probes for neutral and alkaline ceramidases
New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.
research Sexual dimorphism of growth plate prehypertrophic and hypertrophic chondrocytes in response to testosterone requires metabolism to dihydrotestosterone (DHT) by steroid 5‐alpha reductase type 1
Male cells need DHT to respond to testosterone, while female cells do not.
research Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss
Blocking adenosine A2B receptor may prevent or treat hearing loss.
research Targeting of Smoothened for therapeutic gain
Targeting the Smoothened receptor shows promise for treating certain cancers.
research 921 Generation of a new rodent model of scleroderma
Researchers created a new mouse model for studying scleroderma.
research The role of androgen and androgen receptor in skin-related disorders
Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.
research Spatiotemporal Expression, Distribution, and Processing of POMC and POMC-derived Peptides in Murine Skin
POMC-derived peptides are important for skin functions like immune response and stress management.
research 176 Characterising Neurotransmitter Signalling in Human Skin and Hair Follicles
Skin and hair cells release serotonin and histamine naturally, which could help improve skin health.
research A new species ofAplodontopus(Acari: Astigmata: Chortoglyphidae) from the yellow-bellied marmot,Marmota flaviventris(Rodentia: Sciuridae) in Eastern Washington, USA, with observations on its pathology
Researchers found a new mite species causing severe hair loss and skin problems in yellow-bellied marmots.
research Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair
Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.
research c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
research Androgens/Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
research Mouse notch: expression in hair follicles correlates with cell fate determination.
Mouse Notch is important for determining cell roles in hair follicles.
research The androgen receptor gene polyglycine repeat polymorphism is associated with memory performance in healthy Chinese individuals
Certain gene variations are linked to better memory in healthy Chinese women.
research The investigation of selective sphingosine-1 phosphate receptor 1&4 modulator to treat alopecia areata mouse model
NXC736 significantly reduced hair loss in mice with alopecia areata.
research Dermal Papilla Cells from Human Hair Follicles Express mRNA for Retinoic Acid Receptors in Culture
research Evidence for multiple, developmentally regulated isoforms of Ptprq on hair cells of the inner ear
Ptprq has multiple forms that change during inner ear development.