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Activating cannabinoid receptor 1 reduces certain keratin levels, potentially aiding psoriasis treatment.

Semecarpus anacardium leaf extract fights breast cancer and extends survival in mice.

EGFR hyperactivation increases sebaceous gland size and sebum production in mice.

Mutations in Far2 mice cause hair loss due to sebaceous gland issues.

All-trans-retinoic acid stops mink hair growth by affecting cell growth and causing cell death.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.

Muscles can make their own androgens, which may help muscle growth.

Alopecia areata involves unique activation of certain immune cells.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Aryl hydrocarbon receptor overexpression found in miniaturized hair follicles in female hair loss.

Neurosteroids regulate synaptic inhibition in the spinal cord and may help manage spinal pain.

These migraine prevention drugs can cause side effects like constipation, hair loss, injection site reactions, fatigue, and sometimes unexpected issues like Raynaud's phenomenon and weight gain.

Moose have unique interdigital glands with green hairs and larger glands during mating season.

A new model helps study acne and test treatments.

Transglutaminases work through a ping-pong mechanism, and human plasma and platelet transglutaminases have similar catalytic subunits.

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

Gene knockout mice developed scars similar to human hypertrophic scars, useful for studying scar progression.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

A gene mutation worsens skin irritation in mice due to a lack of certain fats.

Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

PP2Acα is essential for proper hair and skin development.

Most patients with dermatomyositis had skin rash, itching, and muscle weakness, treated mainly with prednisolone and hydroxychloroquine.

LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.

A heterozygous mutation in HTRA1 can cause severe CARASIL symptoms.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.

Endothelin-1 helps amelanotic melanocytes stick and move better on certain proteins.

Dystonia may be part of PAS-4 and linked to immune issues.