research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
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research XEDAR activates the non-canonical NF-κB pathway
XEDAR triggers a specific signaling pathway in cells.
research Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives
Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
research Intravital longitudinal wide-area imaging of dynamic bone marrow engraftment and multilineage differentiation through nuclear-cytoplasmic labeling
Transplanted bone marrow cells actively move, form clusters, and grow after transplantation.
research High frequency of cutaneous manifestations including vitiligo and alopecia areata in a prospective cohort of patients with chronic graft-vs-host disease
Patients with chronic graft-versus-host disease often have skin problems like vitiligo and alopecia areata.
research Phytochemical, Toxicological and Pharmacological Studies of <i>Asiasari Radix</i> et Rhizoma: A Review
Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.
research Stem Cells in the Wild: Understanding the World of Stem Cells through Intravital Imaging
Intravital imaging helps us better understand stem cells in their natural environment and could improve knowledge of organ regeneration and cancer development.
research REVIEW OF SO-CALLED ASEPTIC NEUTROPHILIC DERMATOSES
The review says skin conditions with sterile pustules need more research for better treatments.
research Alopecia Areata of the Beard: A Review of the Literature
The document concludes that more research is needed to understand and treat Beard Alopecia Areata due to limited current knowledge and evidence.
research Skin Hyperpigmentation and Increased Angiogenesis Secondary to Vitamin B12 Deficiency in a Young Vegetarian Woman
Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.
research Skin diseases in consequence of endocrine alterations
Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
research The promise and challenges of cell therapy for psoriasis*
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research Targeting host cell proteases as a potential treatment strategy to limit the spread of SARS‐CoV‐2 in the respiratory tract
Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.
research Applications and Implications of Heparin and Protamine in Tissue Engineering and Regenerative Medicine
Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.
research Recent updates on Wnt signaling modulators: a patent review (2014-2020)
New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
research Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
research LncRNA-PCAT1 maintains characteristics of dermal papilla cells and promotes hair follicle regeneration by regulating miR-329/Wnt10b axis
PCAT1 helps hair growth by controlling miR-329/Wnt10b.
research Compilation of a comprehensive gene panel for systematic assessment of genes that govern an individual’s drug responses
Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
research Doxorubicin-induced hair loss in the Angora rabbit: a study of treatments to protect against the hair loss
Vitamin E in the diet might help protect against hair loss caused by the chemotherapy drug doxorubicin in rabbits.
research Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs
Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.
research Regulatory effect of β-catenin on proliferation of hair follicle stem cells involves PI3K/Akt pathway
β-catenin helps hair follicle stem cells grow by activating a specific cell pathway.
research Drug eruptions in dermatology
Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.
research An antimicrobial microneedle patch promotes functional healing of infected wounds through controlled release of adipose tissue-derived apoptotic vesicles
The microneedle patch helps heal infected wounds quickly and without scars.
research Wnt is back in drugmakers' sights, but is it druggable?
Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.
research Generation of Pax1/PAX1-Specific Monoclonal Antibodies
Researchers created specific antibodies that detect a protein important in development and various conditions, and can be used for research and diagnosis.
research Madarosis, milphosis, eyelash trichomegaly, and dermatochalasis
The document concludes that changes in eyelashes and eyelid skin can indicate various local and systemic diseases.
research Bendamustine: an Old Drug in the New Era for Patients with Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia
Bendamustine, often combined with other drugs, is effective and less toxic for certain blood cancers, but less effective for young, fit patients with CLL.
research Successive Release of Tissue Inhibitors of Metalloproteinase-1 Through Graphene Oxide-Based Delivery System Can Promote Skin Regeneration
Graphene oxide helps deliver a skin healing agent over time, improving skin and hair follicle regeneration.
research Dasatinib-Induced Leukotrichia in a Patient With Chronic Myelogenous Leukemia
A woman's hair turned white after taking a cancer drug called dasatinib.
research Stem Cells Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies
Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.