667 citations
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May 2008 in “Genes & Development” Histone demethylases can change gene expression and may be linked to diseases like cancer.
245 citations
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January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
151 citations
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November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
74 citations
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June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
67 citations
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September 2003 in “Journal of cutaneous pathology” Skin problems are very common in people with end-stage kidney disease.
66 citations
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January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
66 citations
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October 1984 in “Annual Review of Microbiology” Toxic Shock Syndrome cases increased due to new factors, but decreased with public health measures and changes in tampon use.
61 citations
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October 2010 in “Postgraduate Medical Journal” Most patients with chronic kidney disease have skin problems, which get worse as the disease progresses, and dialysis doesn't greatly reduce these issues.
59 citations
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June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
50 citations
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November 2010 in “Plastic and Reconstructive Surgery” Botox increased hair count in men with baldness and might work by improving scalp blood flow.
47 citations
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March 2019 in “Journal of immunology research” Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
45 citations
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October 2014 in “Stem cell research & therapy” Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.
45 citations
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July 2009 in “Journal of Investigative Dermatology” The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
35 citations
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October 2017 in “Trends in Molecular Medicine” Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.
31 citations
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September 2016 in “PLoS ONE” Cell division orientation varies by body site and is linked to epidermal thickness and cell density.
27 citations
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November 2021 in “Scientific Reports” Men are more affected by COVID-19 due to differences in immune responses and protein expression.
27 citations
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March 2018 in “Biomaterials” Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
17 citations
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June 2015 in “PLOS ONE” FDG PET/CT scans can change cancer treatment plans for dogs.
11 citations
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April 2013 in “Journal of Proteomics” Found different proteins in balding and non-balding cells, giving insight into hair loss causes.
9 citations
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January 2015 in “Fundamental & clinical pharmacology” Cyclosporine A helps hair grow by blocking a process that would otherwise cause hair cells to die.
6 citations
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May 2020 in “Pharmacology Research & Perspectives” A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.
4 citations
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April 2021 in “Experimental and Molecular Medicine” The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.
4 citations
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December 2009 in “Elsevier eBooks” Breadfruit is nutritious and has potential health and medicinal benefits, but is currently underused.
3 citations
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January 2014 in “Elsevier eBooks” Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
2 citations
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January 2014 in “Elsevier eBooks” The document concludes that reactivation of herpesviruses, especially HHV-6, is linked to severe symptoms and complications in drug-induced hypersensitivity syndrome.
December 2023 in “Intisari Sains Medis” SLE and DM can coexist but are rare and need careful evaluation.
August 2022 in “Frontiers in genetics” A new genetic change in the DSC3 gene is linked to a rare condition causing hair loss and skin blisters in a child.
Low-level laser therapy may help stem cells grow and function better, aiding in healing and tissue repair.
August 1994 in “Molecular Endocrinology” Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
December 2025 in “Scientific Reports” Valproic acid helps hair follicle stem cells survive better in low oxygen and glucose conditions.