247 citations
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August 2011 in “European Journal of Epidemiology” The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.
220 citations
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March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
219 citations
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September 2009 in “European journal of epidemiology” The Rotterdam Study aims to understand various diseases in older adults.
209 citations
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March 1989 in “Journal of The American Academy of Dermatology” Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.
198 citations
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July 2011 in “Cochrane library” Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.
139 citations
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December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
133 citations
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May 2016 in “Cell Host & Microbe” Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
130 citations
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September 2018 in “Cell Reports” Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.
124 citations
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June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
112 citations
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November 2023 in “Nano-Micro Letters” Nanozymes show promise for effective and safe cancer treatment.
106 citations
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September 2010 in “Stem cells” Skin-derived precursors in hair follicles come from different origins but function similarly.
97 citations
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March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
76 citations
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January 2019 in “Nanoscale” Created material boosts hair growth and kills bacteria for wound healing.
64 citations
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August 2019 in “Circulation” ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.
64 citations
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August 2014 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.
62 citations
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April 2008 in “Neurobiology of aging” Scientists found a gene in mice that causes early hearing loss.
62 citations
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January 2000 in “Developmental dynamics” Notch-related genes play a key role in the development and cycling of hair follicles.
61 citations
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May 2015 in “Planta” Certain fungi and bacteria help orchid seeds germinate and plants grow better.
56 citations
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February 2010 in “PLOS ONE” Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
55 citations
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April 2010 in “Cancer and Metastasis Reviews” TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
48 citations
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February 2016 in “Scientific Reports” Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
48 citations
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June 2014 in “Neurobiology of Disease” The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.
46 citations
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September 2013 in “PLOS ONE” Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.
45 citations
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September 2012 in “Life Sciences” Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.
38 citations
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January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
37 citations
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October 2013 in “PLoS ONE” MicroRNAs play a key role in wool growth in Tibetan sheep.
36 citations
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July 2016 in “Scientific reports” People's decision-making can be influenced by their internal biological clocks, as shown by gene expression, not just self-reported preferences for morning or evening.
34 citations
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July 2018 in “American Journal of Physiology-heart and Circulatory Physiology” Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.
31 citations
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January 2010 in “GenomeBiology.com (London. Print)” The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.
31 citations
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January 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.