research Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation
Applying a specific inhibitor lightens skin and hair color.
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research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
research Kin‐cohort analysis of LRRK2‐G2019S penetrance in Parkinson's disease
The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.
research A preliminary study of finasteride in Tourette syndrome
Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.
research Adaptations in the structure and innervation of follicle‐sinus complexes to an aquatic environment as seen in the Florida manatee (Trichechus manatus latirostris)
Manatee whiskers are specially adapted for touch in water.
research Malignancy and Cancer Treatment-Related Hair and Nail Changes
Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.
research Analysis of Protein Interactions by Surface Plasmon Resonance
Surface Plasmon Resonance is a useful tool for studying protein interactions and has potential for future technological advancements.
research Desferrioxamine treatment of aceruloplasminemia: Long‐term follow‐up
Finasteride may help reduce symptoms in male Tourette syndrome patients.
research Methods for quantifying intrafollicular drug delivery: a critical appraisal
The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
research Clinical features, with video documentation, of the original familial lewy body parkinsonism caused by α‐synuclein triplication (Iowa kindred)
The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.
research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine
Hair follicles are valuable for regenerative medicine and wound healing.
research Hairless Modulates Ligand-Dependent Activation of the Vitamin D Receptor-Retinoid X Receptor Heterodimer
Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
research Minoxidil specifically decreases the expression of lysine hydroxylase in cultured human skin fibroblasts
Minoxidil reduces lysine hydroxylase in skin cells.
research Physical methods for topical skin drug delivery: concepts and applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
research Immunolocalization of a Histidine-Rich Epidermal Differentiation Protein in the Chicken Supports the Hypothesis of an Evolutionary Developmental Link between the Embryonic Subperiderm and Feather Barbs and Barbules
A specific protein in chicken embryos links early skin layers to feather development.
research Effect of minoxidil on rabbit lens epithelial cell behavior in vitro and in situ
Minoxidil may help prevent capsular opacification after cataract surgery.
research Trichoscopy of Dark Scalp
Trichoscopy helps diagnose hair and scalp disorders in dark-skinned people by identifying unique patterns.
research The Expression of Vitamin D-Upregulated Protein 1 in Skin and its Interaction with Sciellin in Cultured Keratinocytes
VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.
research Pathological findings in a case of stiff person syndrome with anti‐GAD antibodies
Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.
research Biology of Human Hair: Know Your Hair to Control It
Understanding hair biology is key to developing better treatments for hair and scalp issues.
research Histological evaluation of hair follicle due to papain's depilatory effect
Papain cream removes hair better than papain gel, causing hair follicles to widen and skin to thicken.
research Androgenetic alopecia
Various treatments exist for hair loss, but more research is needed for better options.
research Proteomic Characterization of Damaged Single Hairs Recovered after an Explosion for Protein-Based Human Identification
Explosions don't stop hair proteins from being used to identify people.
research No evidence for THAP1/DYT6 variants as disease modifiers in DYT1 dystonia
THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.
research Molecular evolution of HR, a gene that regulates the postnatal cycle of the hair follicle
Changes in the HR gene have influenced hair growth and may lead to hair loss conditions in humans.
research Mutation in 5′ upstream region of GCH I gene causes familial dopa-responsive dystonia
A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.
research Topical Minoxidil in the Treatment of Male Pattern Alopecia
Minoxidil can help thicken hair in some people with male pattern baldness, especially if used early and continuously.
research Bioequivalence Study of Finasteride
Finasteride's two formulations absorb similarly, showing bioequivalence.
research Repigmentation of leukoderma in a piebald patient associated with a novel c-KIT gene mutation, G592E, of the tyrosine kinase domain
A new gene mutation may allow some piebaldism patients to regain skin color in white patches.
research Ability to cycle despite severe freezing of gait in atypical parkinsonism in Fahr's syndrome
Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.