1308 citations
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March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
520 citations
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January 2017 in “AIMS biophysics” Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.
508 citations
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February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
343 citations
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December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
195 citations
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January 2008 in “Photochemistry and Photobiology” Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.
158 citations
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May 1968 in “The journal of nutrition/The Journal of nutrition” Zinc is crucial for growth and health in rats.
137 citations
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October 2009 in “The American journal of pathology” Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
131 citations
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January 2018 in “Scientific Reports” Mycorrhiza helps trifoliate orange grow better roots and handle drought.
130 citations
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January 2017 in “International journal of nanomedicine” Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
108 citations
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December 2003 in “Lasers in surgery and medicine” ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.
104 citations
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May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
75 citations
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May 2013 in “Journal of the American Academy of Dermatology” Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.
57 citations
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December 2021 in “Nature Communications” Non-canonical Wnt signaling helps intestinal stem cells move to injury sites for tissue repair.
47 citations
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November 2012 in “Pharmaceutical research” Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
40 citations
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August 2018 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
36 citations
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March 2014 in “Biomaterials” A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.
35 citations
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January 2018 in “Skin pharmacology and physiology” Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
35 citations
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July 2009 in “Optics express” Researchers created a new light source that improves chemical imaging by removing background noise.
32 citations
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December 2017 in “International Journal of Molecular Sciences” Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.
32 citations
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April 2013 in “Anais Brasileiros de Dermatologia” The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.
29 citations
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September 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.
26 citations
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March 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia” The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.
26 citations
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January 1978 in “Nephron” Minoxidil lowers blood pressure effectively but may cause side effects.
25 citations
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May 2020 in “EMBO reports” Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
25 citations
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July 2019 in “Journal of drug delivery science and technology” Researchers created better skin-application menthol capsules that are stable, safe, and penetrate the skin quickly.
24 citations
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June 2021 in “Agronomy” Protein hydrolysates applied to roots or leaves differently improved lettuce yield and quality, with the best results seen in specific combined treatments for each type.
24 citations
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June 2018 in “Expert Review of Pharmacoeconomics & Outcomes Research” Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.
24 citations
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February 1987 in “Drugs” Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.
20 citations
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October 2017 in “Clinical Endocrinology” The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.
15 citations
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November 2019 in “Cutaneous and Ocular Toxicology” Minoxidil tretinoin liposomal based hydrogel shows promise for effective treatment of hair loss by delivering both drugs at the same time.