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Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.

15d‐PGJ2 cream protects against UVB-induced skin damage in mice.

New genes and pathways are important for testosterone production and male sexual development.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Human liver enzyme DHEA ST helps process minoxidil.

Nonclassic 21-hydroxylase deficiency is a common, treatable genetic disorder causing reversible symptoms like acne and hair loss.

Progesterone affects GABA_A receptor function by altering δ subunit levels.

Masculinization in affected individuals occurs gradually after puberty due to hormone changes.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Estrogen deficiency can reduce the enzyme activity needed to activate vitamin D.

In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.

Blocking a protein called prostaglandin D2 might help treat hair loss.

Certain genetic variants reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia.

Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

A genetic mutation in a specific gene causes a salt-wasting condition in a Pakistani girl and her family.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Progesterone and its metabolites affect myelin protein expression differently in male and female rat Schwann cells.

In STSD patients, the body compensates for low androgen levels by increasing another enzyme's activity.

Enzyme activities do not cause early pubic hair in these girls.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.

Prostaglandin D2, found in higher levels in bald scalps, stops hair growth, suggesting that blocking its receptor could potentially treat hair loss.

A substance called prostaglandin D2 is found more in bald scalps and it stops hair from growing. Blocking its receptor could potentially treat hair loss.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.