1398 citations
,
May 2008 in “Histochemistry and Cell Biology” Keratins are crucial for cell stability, wound healing, and cancer diagnosis.
114 citations
,
January 2007 in “Drug Safety” Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.
43 citations
,
November 2007 in “Dermatologic Clinics” Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.
18 citations
,
March 2004 in “Clinics in Dermatology” Lupus can cause hair loss and nail changes, with treatments available for both.
7 citations
,
June 2015 in “Cutaneous and Ocular Toxicology” Some drugs can cause skin reactions, which may improve when the drug is stopped, and rapid diagnosis and stopping the drug is crucial.
7 citations
,
May 2014 in “Clinical practice” Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.
1 citations
,
July 2016 in “British Journal of Dermatology” Men with a certain type of hair loss often use facial moisturizers, and a specific antibiotic treatment may help another hair condition.
Lichen planopilaris and frontal fibrosing alopecia are likely the same disease with different clinical appearances.
1 citations
,
October 2019 in “International journal of contemporary pediatrics” A 12-year-old boy with twenty nail dystrophy, a condition affecting all nails, was treated conservatively due to its self-limiting nature and good prognosis.
26 citations
,
October 2016 in “Case Reports in Dermatology” A man with severe hair loss saw hair and nail improvement after 10 months on tofacitinib without side effects.
8 citations
,
April 2017 in “International Journal of Dermatology” Applying 5% minoxidil to fingernails can significantly increase their growth rate.
July 2017 in “British Journal of Dermatology” The document concludes that scalp conditions have various causes and can present in many different ways.
80 citations
,
June 2020 in “Dermatopathology” COVID-19 can cause various skin lesions, which may result from the virus and immune response, and are not directly linked to illness severity.
78 citations
,
April 1994 in “Archives of dermatology” The study found that Keratosis Pilaris Atrophicans is a genetic skin condition that starts in childhood, involves inflammation and scarring, and current treatments are only somewhat effective.
4 citations
,
August 2018 in “Journal of The American Academy of Dermatology” The authors agree that biotin may help certain hair disorders but lacks evidence for use in healthy people and call for more research.
6 citations
,
February 2015 in “Dermatologic Surgery” The document concludes that a new training model could improve dermatology residents' skills in nail procedures and lead to more nail cases being treated by dermatologists.
30 citations
,
October 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.
21 citations
,
October 1980 in “Gastroenterology” The report described a unique case of Cronkhite-Canada syndrome with unusual polyps and an association with multiple myeloma.
1 citations
,
January 2019 in “Przegla̧d dermatologiczny” Skin problems like psoriasis and systemic sclerosis can increase the risk of heart disease, so doctors should watch for heart risks in patients with these conditions.
October 2023 in “Dermatology practical & conceptual” Pulse corticosteroids help regrow hair in alopecia areata but have side effects, especially betamethasone.
April 2013 in “Journal of the American Academy of Dermatology” Diabetic patients often have ingrown nails due to obesity, high blood pressure, past injuries, bad nail trimming, nail fungus, weak foot pulse, and weak knee reflex.
Iron supplements may reverse premature graying in iron-deficient individuals; ingrown nails are common in diabetics with certain risk factors; topical finasteride may reduce scalp DHT as effectively as oral finasteride; monilethrix treatment is challenging but some medications can help.
64 citations
,
June 1992 in “International Journal of Dermatology” Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.
19 citations
,
August 2020 in “Gastroenterology report” There is no standard treatment for the rare Cronkhite–Canada syndrome, which can be fatal and lead to cancer.
2 citations
,
October 2016 Chemotherapy and radiotherapy can cause skin side effects like rashes, hair loss, and nail changes, which are usually managed with conservative treatments.
87 citations
,
December 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Cancer patients treated with immune checkpoint inhibitors may develop alopecia, but some hair regrowth is possible with treatment.
55 citations
,
February 2013 in “The Anatomical Record” Mouse nails are similar to human nails, making them useful for studying nail diseases.
29 citations
,
October 2012 in “Anais Brasileiros De Dermatologia” Diagnosing hair loss disorders needs clinical, dermoscopic, and histological differences, and checking menstrual cycle, weight changes, drug therapy, and nail changes.
18 citations
,
August 2018 in “The FASEB journal” Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.
4 citations
,
December 2001 in “Endoscopy” Prednisolone and Bactrim improved symptoms in a woman with Cronkhite-Canada syndrome.