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Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

Excessive selenium from a supplement caused toxicity but patients recovered with care.

HOXC13 is essential for hair and nail development by regulating Foxn1.

Keratin films from human hair can potentially replace human nail plates for drug testing.

Skin problems are very common in people with end-stage kidney disease.

Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.

Most patients with chronic kidney disease have skin problems, which get worse as the disease progresses, and dialysis doesn't greatly reduce these issues.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

Nearly all elderly nursing home residents had a skin disease, with dry skin being the most common.

Chemotherapy can cause various skin problems, and recognizing them helps improve patient care.

HIV can cause various nail and hair disorders, important for early diagnosis and treatment.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Lupus can affect the scalp and nails, often causing hair loss and nail damage, and needs early aggressive treatment to prevent permanent damage.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

A special hydrogel helps heal skin without scars and regrows hair.

Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.

Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.

Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.

FOXN1 mutations can cause varying immune and physical issues, with severity influenced by gene activity and possibly other factors.

Adults with certain skin conditions may have higher levels of inflammation in their body.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

First Korean case of Cronkhite-Canada syndrome with colon cancer and serrated adenoma.

Dermoscopy now helps diagnose various skin, hair, and nail issues, improving patient care and treatment understanding.

Non-immune factors play a significant role in alopecia areata.

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.