research Androgens and hair: a biological paradox with clinical consequences
Androgens can both increase body hair and cause scalp hair loss.
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research Diseases of Periocular Hair
The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.
research Cutaneous transcriptome analysis in NIH hairless mice
Key genes linked to hair growth and cancer were identified in hairless mice.
research Comparative Gene Expression Profiling of Senescent and Androgenetic Alopecia Using Microarray Analysis
SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.
research Histomorphometrical Characterization of Skin of Native Cattle (Bos indicus) in Bangladesh
Male cattle skin is better for quality leather production.
research Medical consequences of long-term anabolic-androgenic Steroids (AASs) abuses in athletes
Long-term steroid abuse in athletes causes serious health risks, outweighing any benefits.
research Guidelines on Hair Restoration for East Asian Patients
Hair restoration for East Asians should consider their unique characteristics like head shape, hair thickness, and hair density, and use modified procedures and treatments to minimize scarring and maintain hair density.
research Analogs of human genetic skin disease in domesticated animals
Some domesticated animals have the same genetic skin diseases as humans, which can help doctors understand human genetic mutations.
research Forensic and Legal Medicine
Forensic medicine is crucial for justice and needs continuous innovation and technology integration.
research Current Genetics in Hair Diseases
Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
research The Skin and Subcutaneous Tissues
The document concludes that skin and nail changes can indicate various underlying health conditions.
research Testosterone and dihydrotestosterone production in genetically furless and furred male rabbits and effects on growth.
Furless male rabbits grew slightly faster and heavier than furred ones, but testosterone levels were not the cause.
research Decay of Skin-Specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.
research Convergent Decay of Skin-specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.
research Cicatricial Alopecia
The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.
research Videodermoscopy Evaluation in Non-scarring Alopecia of Scalp
Videodermoscopy is effective for diagnosing different types of non-scarring hair loss.
research Hypotrichosis congenita (KRT71 mutation) in Hereford cattle in Uruguay
A KRT71 mutation in Hereford cattle in Uruguay causes thin, curly hair and scaly skin.
research Hair Disorders
Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
research Hypotrichosis and Alopecia
Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.
research Impact of plant ecotype on Bacillus-mediated growth promotion
Bacillus amyloliquefaciens can boost root hair growth in some Arabidopsis plants, potentially improving agriculture.
research Healthy Hair: Form and Function
Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.
research Formulation Development and Evaluation of Herbal Hair Oil
Herbal hair oil formulations A4 and A5 effectively promote hair growth and stability.
research UTILIZING ULTRASOUND FOR GENE THERAPY:A PROMISING STRATEGY FOR TISSUE REGENERATION
Ultrasound-assisted gene therapy could revolutionize tissue regeneration by improving gene delivery.
research Characterisation of Myotonic Dystrophy type I cell models and drug evaluation by a cell- based quantification platform.
The study on Myotonic Dystrophy type I (DM1) focuses on characterizing cell models and evaluating potential therapies using a cell-based quantification platform. It highlights the roles of DMPK and MBNL1 proteins in DM1 pathology, where misregulation and sequestration lead to disrupted splicing and multisystemic symptoms. The research identifies antisense oligonucleotides (ASOs) as promising therapeutic agents, capable of increasing MBNL1 protein levels without affecting DMPK protein levels. The study underscores the importance of robust in vitro models and advanced techniques like digital droplet PCR and In-Cell Western for drug screening and understanding DM1's complex molecular mechanisms.
research The role of 3Rs in the age of One Health: where we are and where we’re going
Innovative methods are reducing animal testing and improving biomedical research.
research Psychosocial aspects of androgenetic alopecia
Hair loss can cause significant social and emotional issues, especially for women and young men.
research Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of β-catenin in mice
Wnt signaling is vital for cell growth, development, and cancer research.
research Overweight and Obesity in Children and Adolescents
Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.
research Evidence-Based and Potential Benefits of Metformin in the Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.