research The Possible Involvement of KATP Channels in Cholestatic Pruritus in Mice
KATP channels may help reduce itching in liver disease.
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research Cepharanthine Inhibits Doxorubicin-Induced Cellular Senescence by Activating Autophagy via the mTOR Signaling Pathway
Cepharanthine helps reduce cell aging caused by the cancer drug Doxorubicin by boosting cell cleanup processes.
research Facile One-Pot Synthesis of Substituted Hydantoins from Carbamates
Scientists in India found a safer and efficient way to make a type of medicine called hydantoins from carbamates, which also worked well in making the seizure medicine, Ethotoin.
research Tapinarof cream for atopic dermatitis: Pharmacokinetics, systemic exposure, and preliminary efficacy/safety results
Tapinarof cream at 1% concentration is effective and better tolerated for treating atopic dermatitis than the 2% concentration.
research A nanocomposite competent to overcome solubility and permeation issues of capsaicin and thiocolchicoside simultaneously in gout management: Fabrication of nanocubosomes
The new delivery system could improve pain and inflammation relief in gout.
research Different Ligands of the TRPV3 Cation Channel Cause Distinct Conformational Changes as Revealed by Intrinsic Tryptophan Fluorescence Quenching
Different ligands change the shape of the TRPV3 ion channel in unique ways.
research OPTIMIZATION OF NANO GEL FORMULATION BASED ON BANGKAL (NAUCLEA SUBDITA) WOOD BARK EXTRACT AND ANTIBACTERIAL ACTIVITY AGAINST PROPIONIBACTERIUM ACNES
The nanogel with Bangkal bark extract effectively fights acne-causing bacteria.
research FC054 The liver monoxygenase system in patients with alopecia
Alopecia patients have a less active liver monoxygenase system, which can be treated with photochemotherapy and system inducers.
research Sustained effect of two antioxidants (oxothiazolidine and δ‐tocopheryl glucoside) for immediate and long‐term sun protection in a sunscreen emulsion based on their different penetrating properties
The sunscreen with two antioxidants offers quick and lasting skin protection from sun damage.
research Multiple layers structured polyvinyl alcohol/titanium dioxide@polydopamine/ZIF-8 composite fibers and their minoxidil-loaded composites
research Solid lipid nanoparticles suspension versus commercial solutions for dermal delivery of minoxidil
SLN suspensions work as well as commercial solutions for minoxidil delivery, but are non-corrosive, making them a promising alternative.
research Antiaging effects of equol: A unique antiandrogenic isoflavone metabolite and its influence in stimulating collagen deposition in human dermal monolayer fibroblasts
Equol may help with antiaging and skin health by boosting collagen and blocking certain hormones.
research Pharmacophore Models for Toxicology Prediction
Pharmacophore models can predict liver toxicity and central nervous system toxicity, but they have limitations and specific requirements.
research Nanoparticles enhance therapeutic outcome in inflamed skin therapy
Nanoparticles improve drug delivery and effectiveness in treating inflamed skin.
research FORMULATION AND EVALUATION OF PHYTOSOME LOTION FROM NOTHOPANAX SCUTELLARIUM LEAF EXTRACT FOR HAIR GROWTH
The phytosome lotion made from Mangkokan leaf extract was more effective for hair growth than 2% minoxidil, especially at 30% concentration.
research The influence of Polyquaternium-7 on the hair properties
Polyquaternium-7 improves hair condition.
research Table 1_Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques.xlsx
Jamogenin and other molecules from plants may help treat hair loss.
research Smoothened antagonists for hair inhibition
Two new compounds were found to effectively reduce hair growth in mice.
research A randomized, double-blind controlled clinical study to evaluate the efficacy and safety of minoxidil topical 2% nanosuspension with aqueous base in the treatment of androgenetic alopecia areata
The 2% minoxidil nanosuspension is as effective as the commercial product but safer and easier to use.
research Novel 5α-reductase inhibitors unlinked to depression-like phenotypes in rat model of BPH
research Novel and established potassium channel openers stimulate hair growth in vitromodes of action in hair follicles.: implications for their
Potassium channel openers like minoxidil boost hair growth.
research Developing formulations for drug follicular targeting: Nanoemulsions loaded with minoxidil and clove oil
Nanoemulsions with minoxidil and clove oil effectively target hair follicles for better alopecia treatment.
research Dermatological drugs and cosmetics
Some cosmetics and dermatological drugs can cause allergic reactions and side effects, like skin irritation and systemic issues.
research “Formulation and Evaluation of Minoxidil Fast Dissolving Tablet”
Minoxidil tablets with 6% croscarmellose sodium dissolve quickly and work well.
research Carvone Decreases Melanin Content by Inhibiting Melanoma Cell Proliferation via the Cyclic Adenosine Monophosphate (cAMP) Pathway
Carvone helps treat skin issues by reducing melanin and stopping harmful cell growth.
research 1316 Aqueous extract of Mentha suaveolens induces Nrf-2 activation and expression of antioxidant and detoxifying enzymes in human keratinocyte HaCaT
Mint water extract boosts protective enzymes in skin cells.
research Optimization of menthol-loaded nanocapsules for skin application using the response surface methodology
Researchers created better skin-application menthol capsules that are stable, safe, and penetrate the skin quickly.
research Nucleus‐specific modulation of phasic and tonic inhibition by endogenous neurosteroidogenesis in the murine thalamus
Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.
research Adverse Systemic Reaction to Dinitrochlorobenzene
A man had bad reactions to a hair loss treatment called DNCB.
research Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.