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      5-Alpha-Reductase Inhibitors and Combination Therapy

      research 5-Alpha-Reductase Inhibitors and Combination Therapy

      15 citations , July 2016 in “Urologic Clinics of North America”
      Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.
      Hair Loss

      research Hair loss

      12 citations , May 1989 in “Postgraduate Medicine”
      The document concludes that hair loss is common and can be treated with medications like minoxidil or surgical options, and it significantly affects people's psychological well-being.
      Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways

      research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways

      1 citations , May 2017 in “InTech eBooks”
      Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
      Hormonal Therapy for Acne

      research Hormonal Therapy for Acne

      1 citations , November 1996 in “Journal of Cutaneous Medicine and Surgery”
      Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
      Fundamentals

      research Fundamentals

      November 2018 in “Springer eBooks”
      Finasteride and minoxidil are effective, low-risk treatments for male hair loss, and patient education on these therapies is important.
      Hair Transplantation: Causes, Techniques, and Future Prospects

      research Hair Transplantation

      January 2010 in “Elsevier eBooks”
      Hair transplantation is a treatment for hair loss mainly caused by genetics, with various techniques and potential complications, and results visible after 8-12 months.
      Hair Growth and Rejuvenation: An Overview

      research Hair growth and rejuvenation: An overview

      81 citations , June 2010 in “Journal of Dermatological Treatment”
      The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.
      Abstracts

      research Abstracts

      October 2020 in “Veterinary Dermatology”
      New treatments and diagnostic methods for various animal skin conditions showed promising results.
      Androgens and Hair Growth

      research Androgens and hair growth

      209 citations , September 2008 in “Dermatologic Therapy”
      Androgens can both increase and decrease hair growth in different parts of the body.
      Finasteride

      research Finasteride

      187 citations , January 1994 in “The New England Journal of Medicine”
      Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
      Role of 5α-Reductase in Health and Disease

      research 9 Role of 5α-reductase in health and disease

      101 citations , April 1994 in “Baillière's clinical endocrinology and metabolism”
      5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
      Finasteride

      research Finasteride

      86 citations , July 1993 in “Drugs”
      Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
      Androgen Excess: Investigations and Management

      research Androgen excess: Investigations and management

      82 citations , May 2016 in “Best Practice & Research in Clinical Obstetrics & Gynaecology”
      The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
      An Overview of Alopecias

      research An Overview of Alopecias

      53 citations , March 2014 in “Cold Spring Harbor Perspectives in Medicine”
      The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.
      Finasteride for Female Androgenetic Alopecia

      research Finasteride for female androgenetic alopecia

      51 citations , October 2002 in “British Journal of Dermatology”
      Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
      Novel Inhibitors of 5α-Reductase

      research Novel inhibitors of 5α-reductase

      20 citations , February 2002 in “Expert Opinion on Therapeutic Patents”
      New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
      25 Years of Estrogen Receptor Beta: A Personal Journey

      research 25 years of ERβ: a personal journey

      11 citations , September 2021 in “Journal of molecular endocrinology”
      ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
      Alopecia: The Search for Novel Agents Continues

      research Alopecia - the search for novel agents continues

      11 citations , August 1997 in “Expert Opinion on Therapeutic Patents”
      Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.