1 citations
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September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.
7 citations
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September 2013 in “Tissue engineering. Part A” Hair follicle stem cells can become motor neurons and reduce muscle loss after nerve injury.
11 citations
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September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific group of skin stem cells was found to help maintain hair follicle cells.
137 citations
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April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
9 citations
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January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
76 citations
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February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
63 citations
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April 2010 in “Development” Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
12 citations
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January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
150 citations
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December 2012 in “EMBO Reports” Stem cell self-renewal is complex and needs more research for full understanding.
85 citations
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January 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
36 citations
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October 2015 in “Cell reports” Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
10 citations
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August 2021 in “EMBO Reports” The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.
1 citations
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November 2023 in “iScience” A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
321 citations
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March 2015 in “Nature” Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
23 citations
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October 2021 in “Cell Stem Cell” Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
Current hair regeneration methods show promise but face challenges in maintaining cell effectiveness and creating the right environment for hair growth.
June 2026 in “Scientific Reports” Nestin-expressing hair follicle cells may be useful for nerve repair and regeneration.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
1 citations
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October 2022 in “Scientific reports” Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.
June 2022 in “Research Square (Research Square)” Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
76 citations
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March 2005 in “Cancer Research” Doxorubicin can block blood vessels from hair follicles, reducing skin tumor growth.
7 citations
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December 2015 in “PloS one” Cryopreserved mouse whisker follicles can grow hair when transplanted into nude mice.
11 citations
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March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Old hair follicles grew better when moved to a young environment.
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
26 citations
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September 2012 in “Cell Reports” B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
85 citations
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July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
133 citations
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July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
3 citations
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July 2023 in “Cells” MG53 helps reduce skin damage caused by nitrogen mustard.
19 citations
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August 2024 in “Journal of Translational Medicine” Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.