research Differentiation of nitrogen-fixing nodules of Sesbania rostrata with special reference to oleosomes (lipid bodies)
Oleosomes help cell growth in Sesbania rostrata nodules but don't aid nitrogen fixation.
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research LncRNAs in Secondary Hair Follicle of Cashmere Goat: Identification, Expression, and Their Regulatory Network in Wnt Signaling Pathway
Researchers found that certain RNA molecules might play a role in the growth of Cashmere goat hair.
research 0034 Cross-species insights into hair follicle-T cell interactions in discoid lupus erythematosus: A comparison of human, canine and mouse models using spatial transcriptomics
This study investigates the mechanisms of discoid lupus erythematosus (DLE), a type of scarring hair loss, by comparing human, canine, and mouse models using spatial transcriptomics. In humans, DLE is characterized by perifollicular T cell enrichment and increased expression of CXCR3 ligands, interferon-response genes, and fibrotic markers, indicating immune activation and extracellular matrix remodeling. Canine DLE shows similar immune cell infiltration and gene expression changes, supporting its use as a model for human disease. In mice, CD8+ T cells near hair follicles lead to stem cell depletion and fibrosis. Across species, shared pathways like interferon signaling and complement activation were identified, with potential therapeutic targets such as CFD and S100A8/9. These findings suggest cross-species therapeutic trials could benefit both human and veterinary medicine.
research BindingDB Entry 50021519: Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment.
research Laser capture microdissection as a method for investigating the human hair follicle microbiome reveals region-specific differences in the bacteriome profile
Laser-capture microdissection effectively analyzes hair follicle microbiomes, revealing region-specific bacterial differences.
research Use of Leukocyte Platelet (L-PRF) Rich Fibrin in Diabetic Foot Ulcer with Osteomyelitis (Three Clinical Cases Report)
L-PRF treatment helped heal diabetic foot ulcers effectively.
research Therapeutic Potential of Nerve Growth Factor-Modified Hair Follicle Stem Cells Transplantation in a Rat Model of Alzheimer’s Disease
NGF-modified hair follicle stem cells may help treat Alzheimer's by improving brain function and reducing harmful proteins.
research Immunohistochemical localization of fibroblast growth factor 18 in hair follicles of healthy beagle dogs
FGF18 is present in beagle dog hair follicles, mainly in the inner root sheath.
research A POTENTIAL RELATION BETWEEN TELOGEN EFFLUVIUM AND IRON DEFICIENCY IN ADULT FEMALES
Low iron levels are linked to hair loss in adult women.
research TLR2 regulates hair follicle cycle and regeneration via BMP signaling
TLR2 is important for hair growth and can be targeted to treat hair loss.
research Clinical Application of a New Near-Infrared Light-Emitting Diode with Broader Spectrum for Skin Rejuvenation and Hair Growth Enhancement
The new near-infrared LED device improves skin and hair with no side effects.
research MULTIPLE DEFECTS OF THE HAIR SHAFT IN NETHERTON'S DISEASE.
Netherton's disease causes multiple hair defects.
research A NOVEL NANOGEL FORMULATION OF FINASTERIDE FOR TOPICAL TREATMENT OF ANDROGENETIC ALOPECIA: DESIGN, CHARACTERIZATION AND IN VITRO EVALUATION
The finasteride nanogel could be an effective topical treatment for hair loss.
research Flecainide
A man with lung cancer had skin and eye side effects from erlotinib but continued treatment with symptom improvement.
research Lucio Phenomenon: Sequelae of Neglected Leprosy
Early diagnosis of leprosy is crucial to prevent disabilities and spread, even in non-endemic areas.
research Topical Delivery of Fenugreek Seed Extract Loaded Solid Lipid Nanoparticles Based Hydrogels for Alopecia
Fenugreek seed extract in a nanoparticle gel could be a promising new treatment for hair loss.
research Coexistence of chronic cutaneous lupus erythematosus and frontal fibrosing alopecia
A patient had both chronic cutaneous lupus erythematosus and frontal fibrosing alopecia.
research Dynamic interactions of lymphatic vessels at the hair follicle stem cell niche during hair regeneration
Lymphatic vessels are essential for hair follicle regeneration and growth.
research Faculty Opinions recommendation of Epithelial Wnt ligand secretion is required for adult hair follicle growth and regeneration.
Wnt ligand secretion by hair follicle cells is essential for hair growth and repair.
research Hypopigmentation in frontal fibrosing alopecia
FFA patients have fewer melanocytes and thinner skin compared to others.
research Fractional microneedle radiofrequency - mechanism of action and assessment of safety, effectiveness in the treatment, and possible side effects based on a review of scientific literature
Fractional microneedle radiofrequency is a safe and effective skin treatment with minimal serious side effects.
research Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)–Deficient Canines
Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.
research Laser microporation facilitates topical drug delivery: a comprehensive review about preclinical development and clinical application
AFL is safe and effective for topical drug delivery but needs larger studies and cheaper devices for wider use.
research Inverted follicular keratosis of the ear lobe masquerading as malignancy
Inverted follicular keratosis can look like cancer but is actually a harmless tumor.
research Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins
Fibroblasts can be mistaken for neural cells, so functional validation is needed.
research Changes in fibronectin, laminin and type IV collagen distribution relate to basement membrane restructuring during the rat vibrissa follicle hair growth cycle.
The rat vibrissa follicle can quickly remodel its basement membrane during hair growth, affecting cell signaling and activity.
research FCE 28260, a new 5α-reductase inhibitor: In vitro and in vivo effects
FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
research [Preliminary findings on lectin binding in human follicular epithelium].
Different glycoconjugates are present in the outer and inner root sheaths of human hair follicles.
research Reduced Ferritin, Folate and Vitamin B12 Levels in Female Patients Diagnosed With Telogen Effluvium
Women with telogen effluvium have lower levels of iron, folate, and vitamin B12.
research P‐35 Nonlethal junctional epidermolysis bullosa in a dog
A dog with a hereditary skin condition causing blisters and hair loss survived for a year.