research Thymosin β4 Identified by Transcriptomic Analysis from HF Anagen to Telogen Promotes Proliferation of SHF-DPCs in Albas Cashmere Goat
Thymosin β4 helps increase hair growth in Cashmere goats.
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research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Understanding the biochemical properties of human hair keratins : self-assembly potential and cell response
Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.
research BMI1 is required for melanocyte stem cell maintenance and hair pigmentation
BMI1 is essential for preventing hair greying and maintaining hair color.
research B-Raf and C-Raf Are Required for Melanocyte Stem Cell Self-Maintenance
B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
research In Vitro differentiation of hair-follicle bulge stem cells into synaptophysin-expressing neurons: a potential new approach for neuro-regeneration
Hair follicle stem cells can be turned into neuron-like cells, offering a new way for brain repair.
research Stem Cells from Human Exfoliated Deciduous teeth Promote Hair Regeneration in Mouse
Baby teeth stem cells can help grow hair in mice.
research New insights into the role of Runx1 in epithelial stem cell biology and pathology
Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.
research BMP2-mediated PTEN enhancement promotes differentiation of hair follicle stem cells by inducing autophagy
BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.
research Hox in the Niche Controls Hairy-geneity
Hox genes control hair growth patterns in mammals by regulating stem cell activity in the skin.
research 602 mTORC1 activity controls human scalp hair follicle pigmentation and growth
mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.
research Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway
Exosomes from stem cells help wounds heal faster by affecting specific cell signals.
research Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
Tiny vesicles from stem cells could be a new treatment for healing wounds.
research Restoration of follicular β-catenin signaling by mesenchymal stem cells promotes hair growth in mice with androgenetic alopecia
Stem cells from umbilical cords can help regrow hair in mice with hair loss.
research 910 Transepidermal UV radiation of human scalp skin induces distinctive hair follicle damage, which is mitigated by topical caffeine treatment
Caffeine can protect scalp hair follicles from damage caused by UV radiation.
research Regenerative Biology and Medicine
The book explains the science of tissue repair and regeneration, its medical uses, challenges, and ethical concerns.
research Small molecules and small molecule drugs in regenerative medicine
Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
research A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming
Small molecule IM boosts hair growth by changing stem cell metabolism.
research In vitro Differentiation of Adipose-Derived Stem Cells into Hair Cell-Like Cells in Guinea Pigs
Guinea pig fat stem cells can become hair cell-like cells in a lab.
research Molecular principles of hair follicle induction and morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research Bone vs. fat: Embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
research Comparison of CD146 +/− mesenchymal stem cells in improving premature ovarian failure
CD146 + mesenchymal stem cells are more effective for treating premature ovarian failure.
research Transcriptional and epigenetic mechanisms governing epidermal stem cell regulation
Understanding how certain proteins and genetic changes control skin stem cells is key to treating skin diseases.
research Therapeutic potential of isoproterenol in androgenetic alopecia: activation of hair follicle stem cells via the PI3K/AKT/β-Catenin signaling pathway
Isoproterenol may help treat hair loss by activating hair follicle stem cells.
research Hair Follicle Development in Mouse Pluripotent Stem Cell-Derived Skin Organoids
Scientists grew hair follicles from mouse stem cells in a lab setting.
research Targeted Knockout of β-Catenin in Adult Melanocyte Stem Cells Using a Mouse Line, Dct::CreERT2, Results in Disrupted Stem Cell Renewal and Pigmentation Defects
Removing β-catenin in certain stem cells causes hair whitening and pigmentation issues.
research Mesenchymal stem cell-derived exosomes ameliorate gentamicin-induced vestibular hair cell injury by regulating the SNARE pathway and enhancing autophagy
Stem cell-derived exosomes can help repair ear damage and improve balance and hearing.
research Mesenchymal Stem Cell Exosomes Therapy for Acquired Trichorrhexis Nodosa: A Case Series
MSC exosome therapy improved hair quality in patients with acquired trichorrhexis nodosa.
research Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment
Myc activation reduces skin stem cells by affecting cell adhesion.
research Mechanical stretch induces hair regeneration through the alternative activation of macrophages
Mechanical stretching of the skin can promote hair growth by activating certain immune cells.