research Keratinocyte Cytokine Networks Associated with Human Melanocytic Nevus Development
Keratinocyte cytokines and genetic variations influence the development of moles and skin pigmentation.
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150-180 / 1000+ resultsresearch The Role of Neprilysin in Regulating the Hair Cycle
Neprilysin is important for hair growth regulation.
research Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells
Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
research Promoting axonal regeneration through exosomes: An update of recent findings on exosomal PTEN and mTOR modifiers
Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
research 130 Expression of nidogen1 in basal cell carcinoma
Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.
research Trans glutaminase-mediated cross-linking in mammalian epidermis
research Tissue‐engineering approaches to enhance nerve regeneration during wound healing
Two methods improved nerve regeneration and touch recovery in skin grafts for burn patients.
research Estrogen modulates mesenchymal-epidermal interactions in the adult nipple
Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
research Synthesis of nerve growth factor mRNA in cultures of developing mouse whisker pad, a peripheral target tissue of sensory trigeminal neurons.
A soluble factor in developing mouse whisker pads boosts nerve growth factor mRNA production.
research Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours
research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury
Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
research Developmental Regulation of Prion Expression in Cattle and Mouse Embryonic Stem Cells
PrPC is important for neural differentiation in cattle and mouse embryonic stem cells.
research The use of keratin biomaterials derived from human hair for the promotion of rapid regeneration of peripheral nerves
Keratin from human hair helps nerves heal faster.
research Nelfb promotes dermal white adipose tissue formation through RNA Polymerase II mediated adipogenic gene regulation
Nelfb is crucial for forming skin fat tissue by regulating genes needed for fat cell development.
research Existence of Neural Crest–Derived Progenitor Cells in Normal and Fuchs Endothelial Dystrophy Corneal Endothelium
Neural crest-derived progenitor cells in the cornea could help treat corneal issues without transplants.
research Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins
Fibroblasts can be mistaken for neural cells, so functional validation is needed.
research Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity
research Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation
N-WASP is essential for healthy skin and preventing inflammation.
research Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth
The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
research Epithelial Fibronectin meshwork controls skin regeneration
Fibronectin is essential for hair follicle regeneration by supporting stem cells.
research Neuroimmunomodulation in chronic wounds: an opinion
Improving nerve and immune interactions may help heal chronic wounds.
research DataSheet1.zip
GPC1 is important for hair growth by helping blood vessels form around hair follicles.
research Gate keeping the sebaceous gland
The research found that specific stem cells maintain skin gland openings and that disrupting their activity can cause blockages or early cancer signs, indicating a need for targeted treatments.
research 724 MPZL3 functions as a negative regulator of sebaceous gland size and sebocyte proliferation
MPZL3 protein helps keep sebaceous gland size and cell growth in check.
research Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development.
EGFR is essential for normal hair development and follicle differentiation.
research Editors' Picks
ANp63 is crucial for skin integrity, new filaggrin gene mutations link to eczema, hair can regrow from non-stem cells, sunburns are increasing, and glucocorticoids help treat skin allergies by affecting immune cells.
research Amphiregulin in Fibrotic Diseases and Cancer
Targeting amphiregulin may improve treatment for fibrosis and cancer.
research Pluripotent Hair Follicle Neural Crest Stem-Cell-Derived Neurons and Schwann Cells Functionally Repair Sciatic Nerves in Rats
research Regulation of Semaphorin3A in the process of cutaneous wound healing
Sema3A can both slow and speed up wound healing, depending on its form and combination with EGF.
research Author response: Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma
Keratinocytes can reverse the effects of the GNAQ oncogene, inhibiting melanoma cell growth.