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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Seeing trauma causes fear in mice by lowering their natural fear-reducing hormones.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

Different rat and mouse strains respond differently to stress and alcohol, which may help us understand similar human mechanisms.

Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

Ethanol-induced motor incoordination in rats is not affected by increased neuroactive steroids.

Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Depressed teens have different steroid levels in urine, which may help identify and treat them.

Social isolation changes brain receptors and makes ethanol more impactful.

Short-term diabetes can cause changes in brain steroids, cholesterol balance, and mitochondrial function.

Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.

Gut microbes significantly affect brain steroid levels.

Neurosteroids help protect fetal brains from asphyxia damage.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

A new method accurately measures nine neuroactive steroids in small blood samples, helping to study brain diseases.

Pregnancy reduces anxiety in rats, but finasteride reverses this effect.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.