research Antiandrogens as Therapies for COVID-19: A Systematic Review
Antiandrogens don't help with COVID-19 and aren't recommended.
Search
for
Sort by
Research
630-660 / 1000+ resultsresearch Androgens at the skin surface regulateS. aureuspathogenesis through the activation ofagrquorum sensing
Androgens like testosterone make Staphylococcus aureus skin infections more common in men.
research Therapeutic Strategies to Target the Androgen Receptor
Therapies targeting the androgen receptor are being developed to treat prostate cancer and improve bone and muscle health.
research ANDROGEN METABOLISM AS IT AFFECTS HAIR GROWTH IN ANDROGENETIC ALOPECIA
Androgens, like DHT, affect hair growth and treatments like finasteride may help.
![Discovery of (2S)-N-(6-Cyano-5-(Trifluoromethyl)Pyridin-3-Yl)-3-(6-(4-Cyanophenyl)-3,6-Diazabicyclo[3.1.1]Heptan-3-Yl)-2-Hydroxy-2-Methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment](/images/research/693e7bf6-2325-4ddc-a20f-3470db9f4516/small/25627.jpg)
research Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment
A new topical treatment for hair loss shows strong hair growth effects with low toxicity.
research Regulation of masculinization: androgen signalling for external genitalia development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research Glia-derived steroids modulate epileptogenesis in a model of temporal lobe epilepsy
Neurosteroids from glia cells help control seizure development in epilepsy.
research Role of Androgen in Mesenchymal Epithelial Interactions in Human Hair Follicle
Androgens promote beard growth but cause hair loss in androgenetic alopecia, with TGF-β1 as a potential treatment target.
research Effects of hormonal treatment on dermatological outcome in transgender people: a multicentric prospective study (ENIGI)
Hormonal treatments can change hair and skin in transgender people, but may not fully achieve desired results.
research 17α-Acetoxy-6-bromo-16β-methylpregna-4,6-diene-3,20-dione
A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.
research Literature ReviewThe Gabrin Sign and Role of Androgens in COVID-19 Severity: A Look at 3 Studies
Androgens might play a role in the severity of COVID-19.
research Androgenetic alopecia and COVID ‐19: A review of the hypothetical role of androgens
Possible link between androgens and COVID-19 severity; more research needed.
research Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Involvement of neurosteroids in the control of hypothalamic-pituitary-adrenal axis activity in pregnant sheep under basal and stressful conditions
Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.
research In vitro and In vivo Effects of 17β-N-(4-phenylcarbamoyl) androst-4-en-3- one Derivatives as 5a-reductase Inhibitors on Androgen-dependent Glands
Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.
research Expression of mRNA for androgen receptor, 5alpha-reductase and 17beta-hydroxysteroid dehydrogenase in human dermal papilla cells
Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
research EFFECT OF ANTIANDROGENS ON VALPROIC ACID-INDUCED NEURODEVELOPMENTAL CHANGES IN RATS
Antiandrogens help improve developmental delays caused by valproic acid in rats.
research Sexual Hormones in Human Skin
Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
research Normalized androgen ratio: its application to clinical dermatology
The normalized androgen ratio can help manage conditions with excess androgen activity in women.
research BIOACTIVE AND PERIPHERAL ANDROGENS IN PREPUBERTAL SIMPLE HYPERTRICHOSIS
Girls with prepubertal simple hypertrichosis have higher dihydrotestosterone (DHT) levels.
research Effects of androgen on extracellular vesicles from endothelial cells in rat penile corpus cavernosum
Low androgen levels reduce nitric oxide production in rat penile cells.
research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline
The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
research Recent discoveries and developments of androgen receptor based therapy for prostate cancer
New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
research Paradigm Shift in the Concept of Hormonal Milieu of Prostate Cancer
Prostate cancer risk is not linked to blood testosterone levels.
research Androgen replacement therapy in women
Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.
research ANTIANDROGEN THERAPY IN DERMATOLOGY
Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
research Neurosteroid influence on affective tone
Endogenous neurosteroids may set a baseline mood.
research Endocrine Aspects of Female Sexual Dysfunction
Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.
research 1116 Novel androgen receptor degrader for androgenetic alopecia (AGA) application
A new treatment for hair loss shows promise with fewer side effects.
research Hormonal Parameters in Androgenetic Hair Loss in the Male
Men with male pattern hair loss have different levels of certain hormones compared to men without hair loss.