research Dihydrotestosterone, and Not Testosterone, Enhances the LPS-Induced Inflammatory Cytokine Gene Expression in Human Adipocytes
Dihydrotestosterone boosts inflammation in fat cells more than testosterone.
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720-750 / 1000+ resultsresearch Plasma levels of C19 steroid glucuronides in pre-menopausal women with non-classical congenital adrenal hyperplasia
Women with non-classical congenital adrenal hyperplasia have higher levels of certain steroids, which can be reduced by treatment.
research <i>In-Vitro</i> Effect of Sex Steroids on Mouse Melanoma (B16F10) Cell Growth
Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.
research 13C-NMR study of 4-azasteroids in solution and solid state
4-azasteroids, including finasteride, can inhibit 5α-reductase, helping treat conditions like enlarged prostate and hair loss.
research Androgen Receptor Blockade Induces the Phagocytosis of MRSA and Pseudomonas aeruginosa by Monocyte-Derived Macrophages In Vitro
Blocking androgen receptors boosts macrophages' ability to clear certain bacteria.
research Hormone und Behaarung
Hormones, especially androgens, affect hair growth and can cause hair loss or excess hair in both men and women.
research Behandlung mit Antiandrogenen in der Gynäkologie
Antiandrogen treatments can help with various women's health issues but often require ongoing use.
![Discovery of (2S)-N-(6-Cyano-5-(Trifluoromethyl)Pyridin-3-Yl)-3-(6-(4-Cyanophenyl)-3,6-Diazabicyclo[3.1.1]Heptan-3-Yl)-2-Hydroxy-2-Methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment](/images/research/693e7bf6-2325-4ddc-a20f-3470db9f4516/small/25627.jpg)
research Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment
A new topical treatment for hair loss shows strong hair growth effects with low toxicity.
research Steroidogenesis of the testis – new genes and pathways
New genes and pathways are important for testosterone production and male sexual development.
research Penis Endocrinology
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
research Synthesis and biological evaluation of esters of 16-formyl-17-methoxy-dehydroepiandrosterone derivatives as inhibitors of 5α-reductase type 2
Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
research 5α-reductase isoenzymes mediate stress-exacerbated Tourette-like responses in animal models
Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.
research Androgen treatment in women
Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.
research Supplementary Material for: Dexamethasone, a synthetic glucocorticoid, induces the activity of androgen receptor in human dermal papilla cells
Dexamethasone increases androgen receptor activity in scalp cells, which might explain stress-related hair loss.
research Androgens in female pig reproduction: actions mediated by the androgen receptor
Androgens may improve pig reproduction by enhancing ovulation and litter size.
research Synthesis and Study of Some 17a-aza-D-homo Steroids as 5α-Reductase Inhibitors
The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.
research Neurosteroid allopregnanolone attenuates development of nicotine withdrawal behavior in mice
Allopregnanolone may help prevent nicotine withdrawal symptoms.
research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research Androgen replacement therapy in women
Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.
research More about X‐linked testicular feminization of the mouse as a noninducible (is) mutation of a regulatory locus: 5α‐androstan‐3α‐17ß‐diol as the true inducer of kidney alcohol dehydrogenase and ß‐glucuronidase
A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.
research [Endocrine constellation in androgenetic alopecia in the female].
Androgen receptors significantly affect hair loss in women with androgenetic alopecia.
research Steroids excreted by human skin. I. C19-steroids in axillary hair.
Human skin releases different steroids, with some coming from sebaceous glands and others from sweat glands.
research Novel modulatory effects of neurosteroids and benzodiazepines on excitatory and inhibitory neurons excitability: a multi-electrode array recording study
Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.
research Androgen Therapy for Postmenopausal Women; What is New?
research Evaluation of the rodent Hershberger assay using three reference endocrine disrupters (androgen and antiandrogens)
The assay effectively detects hormonal activity of certain chemicals.
research Higher Levels of Steroidogenic Acute Regulatory Protein and Type I 3β-Hydroxysteroid Dehydrogenase in the Scalp of Men with Androgenetic Alopecia
Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.
research [Hormones--underestimated problem in dermatology. Part I. Diseases connected with excessive androgenisation].
Hormones beyond androgens may cause acne and hair loss.
research Testosterone’s regulation of the HPA axis differs for adolescent and adult male rats
Adolescent male rats release more stress hormones than adults, and testosterone affects them differently.
research [The function of the autonomic nervous system in women with androgenetic alopecia].
Women with androgenetic alopecia have noticeable changes in their autonomic nervous system.
research Dermatology of androgen-related disorders
Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.