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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Neurosteroids help protect fetal brains from asphyxia damage.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Stopping alcohol after long-term use causes anxiety and changes brain chemicals.

Gut microbes significantly affect brain steroid levels.

Chronic ethanol increases certain brain receptor levels, influenced by steroids and protein changes.

Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

A new method accurately measures nine neuroactive steroids in small blood samples, helping to study brain diseases.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Stopping finasteride for male pattern hair loss changes neuroactive steroid levels in the brain and blood.

Different rat and mouse strains respond differently to stress and alcohol, which may help us understand similar human mechanisms.

Ethanol changes GABAA receptor α4 subunit levels through phosphorylation and neuroactive steroids.

Short-term diabetes can cause changes in brain steroids, cholesterol balance, and mitochondrial function.

Allopregnanolone may enhance alcohol's effects on dopamine neurons, influencing addiction risk.

Neurosteroids may help treat disorders with too much dopamine activity.

Depressed teens have different steroid levels in urine, which may help identify and treat them.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.