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Selumetinib causes skin and hair side effects in kids with NF1, affecting treatment and quality of life.

Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.

Childhood obesity is linked to early puberty and affects brain function.

Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.

Most children with epilepsy on antiepileptic drugs experience side effects, especially those on multiple drugs, but these drugs help reduce seizures.

Neurosteroid withdrawal increases seizure frequency in a rat model of catamenial epilepsy.

Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.

Neurosteroids help balance brain signals when certain inhibitions are reduced.

11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.

Low-dose radiation therapy may improve brain function in some Alzheimer's patients and is generally well-tolerated.

Progesterone's anesthetic effects don't rely on progesterone receptors.

TCDD reduces EGF receptor activity and causes various developmental changes in animals.

Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.

Finasteride treatment should be personalized to individual mental profiles.

Blocking allopregnanolone production in mice makes them more anxious after stress, but this can be reversed with a drug that mimics allopregnanolone.

Seborrheic dermatitis affects quality of life and sleep, linked to stress and nervous system changes.

Genetic factors influence growth and brain development in children.

Finasteride may increase anxiety in bright spaces.

GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.

Children with alopecia areata have lower BDNF levels, linked to worse symptoms and quality of life.

Ovarian and stress hormones can change GABA A receptors through neurosteroids.

Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.

Alcohol exposure in late adolescence increases adult drinking in rats, and finasteride doesn't reduce this effect.

Increasing TSPO in the brain reduces anxiety and depression.

5alpha-reductase 2 is crucial for proper male brain development and sexual differentiation.

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

Finasteride use is linked to a higher risk of memory problems.