research Modulation of Electroosmotic Flow through Skin: Effect of Poly(Amidoamine) Dendrimers
Polyamidoamine dendrimers can change the strength and direction of electroosmotic flow through the skin, affecting drug delivery.
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research Atherogenesis: Estrogen Induction of Polysialylated nCAM (PSA-nCAM) Blocks Monocyte Capture by Vascular Endothelial Cells
Estrogen helps prevent artery plaque by stopping monocyte capture in blood vessels.
research Chronic Exposure of 5‐Alpha Reductase Inhibitor in Young Male Rats Induces Not Only Metabolic Disturbance, But Also Depressive‐Like Behaviors as Similar with Obese Condition
Long-term use of a drug for hair loss and prostate issues can cause metabolic problems and depression-like behavior in young male rats.
research Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition
Certain mice without specific receptors or mast cells don't lose hair from stress.
research Effects of Oral Finasteride on Erectile Function in a Rat Model
Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.
research Review for "The Comparative Effects Between Long‐Term and Short‐Term Treatment of Finasteride on Anxiety‐Like and Depression‐Like Behaviors in Early Senescent Male Rats"
research New Insights into the Research of Bioactive Compounds from Plant Origins with Nutraceutical and Pharmaceutical Potential
Plant bioactive compounds are important for health and can help prevent various diseases.
research Impact of One-Week Administration of Dihydrotestosterone in Rat Anterior Pituitary Gland
Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.
research The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway
Quercitrin may help treat Alzheimer's by boosting brain cell signaling without causing tumors.
research A New Look at the 5?-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research Differential Gene Expression in Post-Finasteride Syndrome Patients
Gene expression differences in PFS patients suggest a potential organic cause for symptoms.
research Medicinal Chemistry of Drugs with N-Oxide Functionalities
N-oxides are important in medicine for improving drug properties and targeting.
research Allopregnanolone and Induction of Endogenous Opioid Inhibition of Oxytocin Responses to Immune Stress in Pregnant Rats
Allopregnanolone helps control oxytocin levels during pregnancy to prevent preterm labor.
research Effects of halogenated analogues of cortisol and progesterone upon hair growth in castrated mice.
Certain chemical changes to cortisol and progesterone can increase or decrease their ability to inhibit hair growth.
research Neurotrophic Effects of Silibinin on Differentiation of Hair Follicle Stem Cells to Neurons
Silibinin at 0.5 μg/ml helps hair follicle stem cells turn into neurons.
research Trazodone and chlorpromazine a proposal treatment for syndrome post-finasteride and syndrome of post-selective serotonin reuptake inhibitors (post-SSRI)
Trazodone and Chlorpromazine might help treat sexual dysfunction from finasteride and SSRIs.
research 51012 Clinical and pathophysiological study of seborrheic capitis: focus on brain-skin connection
Seborrheic dermatitis affects quality of life and sleep, linked to stress and nervous system changes.
research Problems Associated with the Recognition and Confirmation of Low-Dose Endocrine Toxicities
Confirming low-dose endocrine toxicities is difficult and requires more research.
research The human gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs
The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
research CSF 5-HIAA as a predictor of treatment response in trichotillomania.
Higher CSF 5-HIAA levels may predict better response to serotonin re-uptake inhibitors in trichotillomania.
research Cancer Chemotherapy: A Review Update of the Mechanisms of Actions, Prospects, and Associated Problems
Chemotherapy targets all dividing cells, causing side effects like nausea and hair loss.
research Post-finasteride syndrome
Post-finasteride syndrome causes sexual, physical, and psychological symptoms, but more research is needed to understand its causes and connection to finasteride.
research Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth
Stress can cause hair loss by affecting nerve-related hair growth, and noradrenaline might help prevent this.
research Dynamic spatiotemporal coordination of neural stem cell fate decisions through local feedback in the adult vertebrate brain
Neural stem cells use local feedback to maintain balance in the adult brain.
research Eph Receptors and Ephrins: Therapeutic Opportunities
Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
research Multiple sclerosis disease-modifying therapies: adverse effect surveillance and management
The document concludes that managing side effects of MS therapies is crucial for treatment success and patient adherence.
research 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction
Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.
research Pharmaceutical and non-pharmaceutical treatments for migraine: a systematic review of efficacy and safety
Both new medications and non-drug treatments can effectively manage migraines with fewer side effects.
research Aligning Stem Cell Models and Postmortem Studies to Query Striatal Neurodevelopment in Schizophrenia
Schizophrenia risk genes may affect early brain development, contributing to the disease.