November 2024 in “Journal of Investigative Dermatology” Nerve fibers may worsen mast cell activity, leading to abnormal elastic fiber buildup from sun exposure.
10 citations
,
January 2020 in “Acta Neurobiologiae Experimentalis” Valproic acid and crocin together boost cell growth and may help treat nerve injuries.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” PPARγ signaling modulation can protect hair follicle stem cells from chemotherapy-induced damage.
56 citations
,
February 2012 in “Cell Cycle” MicroRNAs are crucial for controlling skin development and healing by regulating genes.
2 citations
,
September 2024 in “Biomedical Research and Therapy” MSCs should be called "master signaling cells" because they mainly help with cell communication and tissue repair.
1 citations
,
January 2015 in “Der pharmacia lettre” Neurosteroids help protect the brain and improve behavior after a stroke in mice.
27 citations
,
April 2017 in “British Journal of Dermatology” Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
January 2000 in “Neuroscience Research”
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Targeting impaired Nrf2 signaling might help treat hidradenitis suppurativa early on.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing UBE2N from skin cells causes inflammation and immune response, which can be lessened with specific inhibitors.
28 citations
,
October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
1 citations
,
January 2005 in “Experimental Dermatology” MC-1R in skin cells may influence inflammation and collagen production.
April 2023 in “Journal of Investigative Dermatology” Disrupting a specific protein's function in hair follicle stem cells triggers their activation and a self-healing process.
8 citations
,
October 2023 in “Frontiers in Immunology” Certain cytokines may cause or be affected by immune skin diseases, suggesting possible new treatments.
April 2023 in “Journal of clinical and translational science” 69 citations
,
May 2009 in “Journal of Investigative Dermatology” Stress might contribute to hair loss in alopecia areata.
1 citations
,
December 2018 in “Sovremennye tehnologii v medicine” Disruptions in Wnt signaling can lead to skin and hair diseases.
Type II spiral ganglion neurites avoid high concentrations of laminin and fibronectin.
74 citations
,
May 2016 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics” Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.
3 citations
,
July 2023 in “International journal of molecular sciences” Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.
70 citations
,
December 2004 in “Proceedings of the National Academy of Sciences” BMP signaling affects hair color by interacting with the MC-1R pathway.
52 citations
,
May 2011 in “Journal of Neuroendocrinology” PEA boosts allopregnanolone production and reduces oxidative stress in brain cells.
3 citations
,
December 2016 in “Springer eBooks” Activating TLR3 improves the healing and immune properties of periodontal ligament stem cells.
132 citations
,
June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
35 citations
,
September 2009 in “Psychoneuroendocrinology” Early-life neurosteroid changes affect adolescent exploration and adult behavior.
September 2025 in “Current Oncology” LncRNAs may help improve brain cancer treatment and diagnosis.
January 2012 in “Journal of Investigative Dermatology” Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.
38 citations
,
January 2017 in “Mediators of Inflammation” Platelet-released growth factors can reduce inflammation in joint disease.
43 citations
,
December 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Progesterone protects neurons from damage by converting to allopregnanolone, which works through GABAA receptors.
1 citations
,
January 2013 in “Digital Scholarship - UNLV (University of Nevada Reno)” Targeting neurosteroids may help prevent drug relapse.