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Children with alopecia areata have lower BDNF levels, linked to worse symptoms and quality of life.
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January 2000 in “Hormone Research in Paediatrics” Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.
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April 1990 in “Journal of comparative neurology” The study found that nerve signals are stronger when there are more connection points, but not necessarily denser, along the nerve's path in the spine.
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March 2006 in “The FASEB Journal” Two methods improved nerve regeneration and touch recovery in skin grafts for burn patients.
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June 2019 in “Psychoneuroendocrinology” Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
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January 2016 NuMA-microtubule interactions are crucial for proper skin structure and hair growth.
Neurosteroids help control dopamine responses in the brain.
A new microneedle patch effectively treats hair loss by delivering growth factors to the skin.
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Activating cannabinoid receptor 1 may help manage psoriasis by reducing certain keratins.
September 2025 in “Figshare” Alopecia areata involves complex immune responses, suggesting broader treatments could help.
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April 2009 in “Journal of Neuroscience Research” HDAC inhibitors help brain cells grow and improve brain function.
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August 2003 in “Journal of comparative neurology” Naked mole-rats have unique skin and hair nerve structures, lacking certain pain and temperature-related neuropeptides.
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December 2024 in “Nano Research” A protein-based hydrogel helps heal diabetic wounds and repair nerves.
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January 2025 in “Pharmaceutical Research” Angelica gigas Nakai root extracts may help with cancer, pain, memory loss, and metabolic issues.
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November 2013 in “PLoS ONE” Estrogen and androgen signals control synaptic changes in rat brains.
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March 2013 in “Journal of Investigative Dermatology” Kv1.3 blockers may help treat alopecia areata and promote hair regrowth.
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September 2021 in “Journal of Neuroendocrinology” Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
September 2024 in “PubMed” Certain RNAs may help diagnose alopecia areata by affecting keratin genes.
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September 2003 in “The Journal of Immunology” Activating PKCα in skin causes cell death and inflammation through different pathways.
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May 2021 in “Scientific Reports” Certain cancer drugs are strongly linked to nerve damage, requiring close monitoring and early treatment.
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April 2009 in “Journal of comparative neurology” P2X3-IR fibers are widespread in rat skin and likely help detect pain.