research Sarcoïdose grave
Severe sarcoidosis often requires long-term systemic corticosteroids and multidisciplinary care, with most patients improving but some experiencing persistent symptoms or complications.
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research Risk:benefit ratio in the treatment of psoriasis with systemic retinoids
Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.
research Additional Benefit Scoring During Health Technology Assessment in Germany - Its Drivers and Impact on Pricing and Discount for Orphan Drugs
Orphan drug benefit scores in Germany are influenced by phase III data and lack of alternatives, but not linked to price or discounts.
research Benefit-Risk Assessment of GLP-1 Receptor Agonists: Implications for Dermatologists and Plastic Surgeons
GLP-1 RAs help with diabetes and skin issues but can cause skin reactions and surgery challenges.
research Green tea: Health benefits
Green tea may help with health issues like cancer, heart disease, and weight loss due to its high catechin content.
research EXPERIENCE WITH ANIFROLUMAB IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS WITH NEUROLOGICAL MANIFESTATIONS
Anifrolumab helped some lupus patients reduce steroid use, but safety concerns remain.
research Testosterone replacement in 49,XXXXY syndrome: andrological, metabolic and neurological aspects
Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.
research Post-Finasteride Syndrome – When will we Get the Courage to Fight the Dictating Pharma Industry – Despite Awareness of “Sexual, Neurological and Metabolic Side Effects in Young Men for Over a Decade”
Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.
research Surgical Anatomy of the Scalp
Understanding scalp anatomy is crucial for successful and safe scalp surgery.
research Surgical Anatomy of the Scalp
Understanding the scalp's five-layer structure is crucial for better surgical outcomes and fewer complications.
research Health Benefits, Antioxidant Activity, and Sensory Attributes of Selected Cold-Pressed Oils
Cold-pressed rapeseed oil is most resistant to oxidation and certain oils may reduce chronic disease risk; consumers like the taste of pumpkin oil best.
research TCM “medicine and food homology” in the management of post-COVID disorders
Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.
research Vitamin B-Complex and its Relationship with the Health of Vegetarian People
Vegetarians should take B vitamin supplements to avoid health issues.
research Insights About a Pandemic: Clinical Approach
The pandemic highlighted the need for accurate information, vaccine development, and adapting to new routines while managing stress and misinformation.
research A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome
The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.
research PKC downregulation upon rapamycin treatment attenuates mitochondrial disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Post-Finasteride Syndrome: An Induced Delusional Disorder with the Potential of a Mass Psychogenic Illness?
PFS might be a delusional disorder with potential to become mass psychogenic illness.
research A machine learning and network framework to discover new indications for small molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research Female sexual dysfunction
Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.
research Comment on “The post-finasteride syndrome: possible etiological mechanisms and symptoms”
Some men experience persistent sexual, neurological, and psychological symptoms after stopping finasteride, but evidence of permanent damage is inconclusive.
research Capsaicin: an in-depth review of its chemical properties, health benefits, and challenges in food applications
Capsaicin offers health benefits and flavor but faces challenges in food use.
research Formulation and Evaluation of PLGA Nanoparticulate-Based Microneedle System for Potential Treatment of Neurological Diseases
The microneedle system shows promise for non-invasive brain drug delivery.
research Role of Phenylalanine and Its Metabolites in Health and Neurological Disorders
Phenylalanine may help with depression but can cause issues if not properly processed.
research Advanced Applications of Vitamin B Complex in Plastic and Cosmetic Surgery: Mechanisms and Therapeutic Benefits
Vitamin B complex improves plastic and cosmetic surgery outcomes by enhancing tissue repair and reducing inflammation.
research Photobiomodulation therapy in management of cancer therapy-induced side effects: WALT position paper 2022
Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.
research Report: Metformin potential in predisposing arthralgia, type II cross reactivity secondary to group A streptococcus infection & other comorbidities in treating PCOS.
Metformin for PCOS can rarely cause side effects like joint pain and behavior changes.
research Teratogenic effect of isotretinoin in both fertile females and males (Review)
Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.
research How Biodegradable Polymers Can be Effective Drug Delivery Systems for Cannabinoids? Prospectives and Challenges
Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.
research An unusual presentation of X-linked adrenoleukodystrophy
A man with X-ALD improved after treatment, highlighting the need to consider X-ALD in similar patients and test their relatives.
research Costunolide—A Bioactive Sesquiterpene Lactone with Diverse Therapeutic Potential
Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.