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September 2014 in “Orphanet Journal of Rare Diseases” Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.
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August 2022 in “ESMO Open” Trastuzumab deruxtecan is effective for HER2-positive breast cancer but requires careful management of side effects.
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October 2020 in “Frontiers in Pharmacology” Targeting endolysosomes may help treat COVID-19.
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January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
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January 2024 in “Burns & Trauma” Engineered extracellular vesicles can improve tissue repair and regeneration.
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September 2015 in “Psychoneuroendocrinology” 5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.
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April 2021 in “International Journal of Molecular Sciences” Curcumin shows promise in reducing pain and inflammation, but more research is needed.
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November 2022 in “Frontiers in Immunology” TLR-targeted therapies show promise in cancer treatment by helping destroy tumors.
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October 2020 in “Arthritis Care & Research” Choosing the right tools is crucial for accurately measuring lupus activity and damage.
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July 2019 in “Journal of Investigative Dermatology” Lack of a key enzyme causes severe skin issues and death in mice.