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Machine learning identified three unique subtypes of androgen excess in women with PCOS, each with different metabolic risks.

A young woman's rare ovarian tumor was successfully removed, improving her hormonal symptoms.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

Sebocytes play a key role in controlling androgen levels in human skin.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Androgens increase norepinephrine release, promoting smooth muscle growth in male sex organs, which may contribute to benign prostatic hypertrophy.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

New progesterone-based compounds can block male hormones.

Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.

Human scalp hair follicles can produce and respond to several hormones, affecting hair growth and pigmentation.

Estrogen affects hair growth and skin cell multiplication.

Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.

Finasteride, a hair loss treatment, works better and is more stable when delivered through specially prepared gels, leading to increased hair growth.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Ethanol changes GABAA receptor α4 subunit levels through phosphorylation and neuroactive steroids.

The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.

CB-03-04 shows promise as a treatment for prostate issues due to its strong anti-androgen effects.

Nerve cells and other cell types work together to start horn growth in dairy goats.

High doses of some contraceptive steroids cause health issues in dogs, but their relevance to humans is unclear.

Low-potency steroids can cause serious side effects in people with skin conditions like Netherton syndrome.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

Metabolite 7 is a strong inhibitor for Alzheimer's disease management.

Steroid cell tumors in the ovary are rare, can produce testosterone causing symptoms, and are mainly treated with surgery.

Mutations in certain receptors can cause diseases and offer new treatment options.

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.