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Ethanol withdrawal reduces the brain's response to certain calming steroids, making seizures harder to control.

Sex and stress steroids quickly change brain cell structures in the hippocampus.

The methods accurately measured brain androgens, showing most 5α-androstane-3α,17β-diol comes from outside the brain, while androsterone is both transported and made in the brain.

2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.

The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.

Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

PEA reduces pain by increasing neurosteroid synthesis in the spinal cord.

Blocking progesterone metabolism can cause depression-like behavior in mice.

Social isolation makes rats more sensitive to alcohol's effects on the brain.

Lower allopregnanolone levels increase stress-related dopamine release in the brain.

Isolation stress in rats reduces brain enzyme levels, affecting dopamine function.

Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.

Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.

Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.

Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.

Finasteride given to baby rats reduces dopamine release and increases alcohol consumption in adult males.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Gene expression differences in PFS patients suggest a potential organic cause for symptoms.

Hormonal contraceptives may reduce social behavior and sexual motivation by lowering allopregnanolone levels.

Targeting neurosteroids may help prevent drug relapse.

Pregnancy affects fear memory and brain activity in female rats.

Finasteride worsens alcohol withdrawal in female mice but eases it in male mice.

Finasteride may cause depression and suicidal thoughts, especially in young men.

Agmatine may help reduce seizures linked to hormone changes in female rats.

Ferulic acid can reduce seizures and depression-like behaviors in catamenial epilepsy by balancing hormones and brain enzyme activity.

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

Neonatal allopregnanolone and stress affect behavior differently in adolescence and adulthood.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.