research Impact of Alpha Blockers, 5-alpha Reductase Inhibitors and Combination Therapy on Sexual Function
Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.
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research Neonatal allopregnanolone or finasteride administration modifies hippocampal K+ Cl− co-transporter expression during early development in male rats
Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.
research Treating psychogenic nonepileptic seizures: Easier said than done
Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.
research Pubertal hormones increase hippocampal expression of α4βδ GABAA receptors
Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.
research Cytoprotective effects of paeoniflorin are associated with translocator protein 18 kDa
Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.
research How Does Altered Metabolism Lead to Seizure Control? Partially Filling the Knowledge Gap
Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.
research Differential Gene Expression in Post-Finasteride Syndrome Patients
Gene expression differences in PFS patients suggest a potential organic cause for symptoms.
research Early postnatal allopregnanolone levels alteration and adult behavioral disruption in rats: Implication for drug abuse
Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.
research Implications of neuroimaging for the treatment of epilepsy
Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.
research Effects of Restraint Stress and Allopregnanolone Inhibition on Amphetamine Locomotor Sensitivity
Targeting neurosteroids may help prevent drug relapse.
research The Plastic and Functional Changes in Hippocampal Neurons During Pregnancy, Delivery and Postpartum are Reversed by Offspring Deprivation
Pregnancy and nursing increase certain brain activities in rats, but these changes disappear when the babies are taken away.
research Sex differences in the effect of finasteride on acute ethanol withdrawal severity in mice : thesis
Finasteride worsens alcohol withdrawal in female mice but eases it in male mice.
research Signal Detection of Depression and Suicidality Associated with Finasteride and Dutasteride: Updated Pharmacovigilance Evidence and Recommendations for Comprehensive Psychiatric Assessment
Finasteride may cause depression and suicidal thoughts, especially in young men.
research Finasteride-Induced Neuropsychiatric Reactions
Finasteride can cause serious mental health issues, so it's advised to avoid it for hair loss.
research Does Propecia Cause More Harms than Good: Assessing Reproductive and Non-Reproductive Effects of Finasteride on Male Health
Finasteride treats hair loss but may cause low libido, erectile issues, and depression.
research Anxiety-, and Depression-like Behaviour Following Short-Term Finasteride Administration is Associated with Impaired Synaptic Plasticity and Cognitive Behaviour in Male Rats
Short-term finasteride use in male rats caused anxiety, depression, and memory problems.
research Ferulic Acid Inhibits Catamenial Epilepsy Through Modulation of Female Hormones
Ferulic acid can reduce seizures and depression-like behaviors in catamenial epilepsy by balancing hormones and brain enzyme activity.
research Nucleus‐specific modulation of phasic and tonic inhibition by endogenous neurosteroidogenesis in the murine thalamus
Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.
research Relationship between neonatal allopregnanolone and neonatal stress: effects on adolescent and adult behaviour /
Neonatal allopregnanolone and stress affect behavior differently in adolescence and adulthood.
research Unraveling the Complex: Changes in Secondary Science Preservice Teachers' Assessment Expertise
Changes in early neurosteroid levels can affect adult learning and anxiety.
research Post-finasteride syndrome
Post-finasteride syndrome causes sexual, physical, and psychological symptoms, but more research is needed to understand its causes and connection to finasteride.
research Mäklare tjugofyrasju : En studie om hur mäklare lyckas kombinera arbete och familjeliv
Neurosteroids help control stress hormone levels in pregnant sheep.
research Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation
Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.
research A Mouse Kindling Model of Perimenstrual Catamenial Epilepsy
Neurosteroids help reduce seizures, but their withdrawal increases seizure activity.
research Glia-derived steroids modulate epileptogenesis in a model of temporal lobe epilepsy
Neurosteroids from glia cells help control seizure development in epilepsy.
research Expanding the therapeutic potential of neuro(active)steroids: a promising strategy for hyperdopaminergic behavioral phenotypes
Neurosteroids may help treat disorders with too much dopamine activity.
research Role of Neurosteroidogenic Pathways in the Antiseizure Activity of Midazolam in the 6‐Hz and Kindling Models of Epilepsy
Midazolam's antiseizure effects are mainly due to synaptic GABA-A receptors, not neurosteroids or extrasynaptic receptors.
research Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output
Lower allopregnanolone levels increase stress-related dopamine release in the brain.
research Anesthetic effects of progesterone are undiminished in progesterone receptor knockout mice
Progesterone's anesthetic effects don't rely on progesterone receptors.
research Design, Synthesis and Anxiolytic Activity Evaluation of N-Acyltryptophanyl- Containing Dipeptides, Potential TSPO Ligands#
The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.