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The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.

In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.

Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Midazolam impairs learning and memory by increasing neurosteroids through specific receptor activation.

Ethanol boosts brain steroid production by activating NMDA receptors, affecting memory formation.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

PEA reduces pain by increasing neurosteroid synthesis in the spinal cord.

EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.

Blocking progesterone metabolism can cause depression-like behavior in mice.

Social isolation makes rats more sensitive to alcohol's effects on the brain.

Lower allopregnanolone levels increase stress-related dopamine release in the brain.

Isolation stress in rats reduces brain enzyme levels, affecting dopamine function.

Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.

Neurosteroids help protect fetal brains from asphyxia damage.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Finasteride use may lead to less alcohol consumption in men with lasting sexual side effects.

Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

Estrogen and androgen signals control synaptic changes in rat brains.

Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Finasteride given to baby rats reduces dopamine release and increases alcohol consumption in adult males.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.