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New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Progesterone protects neurons from damage by converting to allopregnanolone, which works through GABAA receptors.

Allopregnanolone may enhance alcohol's effects on dopamine neurons, influencing addiction risk.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

Progesterone and testosterone protect brain cells from damage through specific pathways.

Progesterone protects brain cells, but Provera does not.

A new method accurately measures nine neuroactive steroids in small blood samples, helping to study brain diseases.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Finasteride can cause sexual problems and depression in young men.

Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.

Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.

Finasteride doesn't affect sleep spindles in men.

Finasteride may protect brain and improve behavior in rats with liver failure.

Early NAS level changes affect alcohol consumption vulnerability.

The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.

Short-term diabetes can cause changes in brain steroids, cholesterol balance, and mitochondrial function.

Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.

A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Steroid sulfatase inhibitors could potentially treat hormone-related disorders like certain cancers, hair loss, acne, and improve cognitive dysfunction.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.