research Understanding the Secular Decline in Testosterone: Mechanisms, Consequences, and Clinical Perspectives
Lifestyle changes and environmental strategies can help address declining testosterone levels.
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90-120 / 920 resultsresearch Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn
Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.
research Mental Health in Visible Skin Disorders: Assessing Anxiety and Depression in vitiligo and alopecia areata patients compared to Healthy Peers
People with vitiligo or alopecia areata have higher anxiety and depression than healthy people.
research Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells
Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
research UV light may induce hypertrichosis through production of PGE2
UV light might cause excessive hair growth by increasing PGE2 in the skin.
research FINASTERIDE IN MODERN MEDICINE: THERAPEUTIC APPLICATIONS AND SYSTEMIC HEALTH IMPLICATIONS
Finasteride is effective for hair loss and prostate issues but may cause lasting side effects.
research Hair stress hormones in individuals with a recent suicide attempt experiencing a depressive episode
People who recently attempted suicide during depression showed signs of adrenal fatigue, but had higher DHEA levels around the attempt time.
research GH-IGF-I axis in non-obese women with functional hyperandrogenism
The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.
research Effects of the α-ketoglutaric acid on the performance, hair follicle development and antioxidant capacity of Rex rabbits
α-Ketoglutaric acid improves hair growth, rabbit performance, and antioxidant levels.
research Macrophages as central mediators of sympathetic neuro-immune interplay in autoimmunity
Restoring nerve-macrophage communication may help treat autoimmune diseases.
research Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease‐associated psychological morbidity
Alopecia areata involves immune system imbalances that may lead to depression and anxiety.
research Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research A COMPREHENSIVE REVIEW ON PHARMACOLOGICAL POTENTIALS OF CAFFEINE
Caffeine boosts alertness, helps breathing, acts as a diuretic, and may aid cancer treatment.
research Repurposing steroidogenesis inhibitors for the therapy of neuropsychiatric disorders: Promises and caveats
Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
research De novo assembly and annotation of Asiatic lion (Panthera leo persica) genome
The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.
research Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity and Alcohol Use Disorders Risk
Neuroactive steroids may affect the risk and treatment of alcohol use disorders.
research Monocyclic Aromatic Compounds
Monocyclic aromatic compounds are important for developing various drugs and treatments.
research Determinants of iron, zinc, and copper concentrations in the hair of dogs and cats
Dogs have more iron and copper in their hair than cats, and outdoor animals have higher iron levels.
research Dehydrogenase, Cortisol, Dopamine, Zinc, and Vitamin D3 in Iraqi Patients with Polycystic Ovary Syndrome
PCOS patients have higher LDH and lower cortisol, dopamine, zinc, and vitamin D3, which may contribute to their symptoms and obesity.
research Vitamin D: A Bridging Element for Wellness; A Case Study on Vitamin D Deficiency and its Association with Alopecia Areata and Other Conditions
Vitamin D is crucial for health, and deficiency can cause hair loss and other health issues.
research Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen
Prolactin affects hair growth cycles and can cause early hair follicle regression.
research A neuroendocrinological perspective on human hair follicle pigmentation
Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
research Hormone therapy in acne
Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
research 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells
Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.
research Finasteride inhibited brain dopaminergic system and open-field behaviors in adolescent male rats
Finasteride affects young male rats' brain function and behavior negatively.
research Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss
Blocking adenosine A2B receptor may prevent or treat hearing loss.
research The Effects of Oral 5-alpha Reductase Inhibitors on Penile Intracavernosal Pressures and Penile Morphology in Rat Model.
Oral finasteride and dutasteride may negatively affect erectile function in rats.
research Efficacy and safety of 5 alpha-reductase inhibitor monotherapy in patients with benign prostatic hyperplasia: A meta-analysis
5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.
research Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition
Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.
research The melanocyte photosensory system in the human skin
Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.