13 citations
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January 2005 in “Chemical and Pharmaceutical Bulletin” Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
11 citations
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November 2022 in “Journal of Endocrinological Investigation” Hormonal treatments can change hair and skin in transgender people, but may not fully achieve desired results.
11 citations
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April 2021 in “Advanced synthesis & catalysis” PXX is an effective and affordable photocatalyst for creating new chemical bonds in organic synthesis.
11 citations
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July 2012 in “Current Opinion in Pediatrics” Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.
11 citations
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September 2010 in “American Journal of Medical Genetics - Part A” A Turkish family with sparse hair and eyebrow loss has a mutation in the U2HR gene linked to Marie Unna hereditary hypotrichosis.
10 citations
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December 2014 in “Journal of Pharmaceutical and Biomedical Analysis” Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
9 citations
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August 2005 in “Experimental Dermatology” Modified pep7, named EPM peptide, effectively promotes hair growth at low concentrations and works well with minoxidil.
9 citations
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November 2004 in “Bioorganic & Medicinal Chemistry Letters” New compounds were made that effectively block enzymes related to prostate issues and hair loss.
8 citations
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January 2018 in “European journal of dermatology/EJD. European journal of dermatology” The girl's regrown brown hair had less of certain pigments than her original black hair.
6 citations
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January 2016 in “Bioorganic & Medicinal Chemistry Letters” Some minoxidil combinations can help differentiate leukemia cells without harming other cells.
6 citations
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April 2014 in “European journal of medicinal chemistry” New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
5 citations
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February 2013 in “Journal of Liquid Chromatography & Related Technologies” Method accurately measures finasteride concentration in medicine.
5 citations
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September 2011 in “Bioorganic & Medicinal Chemistry Letters” Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
5 citations
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February 2010 in “Drug development and industrial pharmacy” Vesicles made of behenyltrimethylammonium chloride and stearic acid can triple the skin absorption of hinokitiol, which may help with hair growth.
5 citations
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October 2009 in “Allergy” Finasteride can cause skin rash.
5 citations
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January 1998 in “Clinical and experimental dermatology” Myotonic dystrophy should be considered in patients with hair thinning, and genetic counseling is important.
4 citations
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January 2025 in “Journal of Materials Chemistry B” The hydrogel effectively treats complex wounds by promoting healing and preventing infection.
3 citations
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August 2017 in “Synlett” Scientists in India found a safer and efficient way to make a type of medicine called hydantoins from carbamates, which also worked well in making the seizure medicine, Ethotoin.
3 citations
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April 2015 in “Cleveland Clinic Journal of Medicine” The woman has scurvy and needs more vitamin C.
2 citations
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January 2018 in “International Journal of Advanced Community Medicine” The cream effectively reduces hyperpigmentation and signs of aging without causing skin irritation.
2 citations
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December 2013 in “Xenobiotica” Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
2 citations
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December 2008 in “Journal of Chemical Crystallography” The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.
2 citations
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October 2004 in “Organic Process Research & Development” The document reviews 20 U.S. patents from July and August 2004 about new drug forms, cancer treatments, aroma chemicals, statin drugs, and various chemical production methods.
2 citations
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September 1980 in “Experientia” Polyethylene alanine caused hair loss in young lab animals but not in adults, with hair regrowth occurring within 20 days.
1 citations
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September 2023 in “Dermatology and therapy” More research is needed to find the best treatment for dissecting cellulitis of the scalp.
1 citations
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August 2020 in “IntechOpen eBooks” Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.
1 citations
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July 2016 in “International Journal of Dermatology” Androgenetic alopecia is less common in Chilean Mapuche than Caucasians, but more common than Asians, with racial differences in prevalence and types.
Finding functions for unknown GPCRs is hard but key for making new drugs.
Monocyclic aromatic compounds are important for developing various drugs and treatments.
January 2025 in “Journal of Pharmaceutical Research Science & Technology” Dissolving microneedles offer efficient, minimally invasive drug delivery through the skin.