June 2026 in “Drug Delivery and Translational Research” The study presents a solid microneedle booster (SMB) as an advanced microneedling platform for treating androgenetic alopecia (AGA). The SMB integrates spring-driven perpendicular stamping with simultaneous liquid dosing, improving microchannel reproducibility and early transport. Tests on porcine skin revealed that SMB achieved greater microchannel surface coverage and deeper penetration than a roller. It also enhanced early-phase permeation, accelerating hair regrowth when combined with minoxidil (MXD) in vivo. Histological analysis showed increased follicle enrichment in the SMB + MXD group. SMB provides a one-step, directionality-controlled microneedling method that enhances early transport and promotes follicular maturation, with potential for broader dermatologic applications.
39 citations
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June 2023 in “Advanced Materials” Microneedles offer a promising, painless, and efficient way to deliver vaccines and therapies directly to the skin.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Biotrinine® may be an effective treatment for chronic hair loss.
February 2026 in “Nano Research” A new microneedle treatment can help regrow hair by improving lymphatic function and metabolism.
20 citations
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October 2023 in “Small” Microneedles show promise for treating hair loss, eye, and mouth diseases.
February 2023 in “Medicine in novel technology and devices” Microneedles with traditional Chinese medicine can help regrow hair in androgenic alopecia.
February 2026 in “Archives of Dermatological Research” Microneedle-delivered polyglutamate effectively and safely improves hair growth in androgenetic alopecia.
81 citations
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July 2012 in “Translational Psychiatry” Memantine may slightly improve memory in people with Down syndrome, but more research is needed.
October 2023 in “Applied materials today” New treatment for hair loss using special microneedles shows promise in reducing inflammation and promoting hair growth.
A new microneedle patch effectively treats hair loss by delivering growth factors to the skin.
5 citations
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January 1998 in “Journal of Toxicologic Pathology” Maneb causes delayed hair follicle damage in rats.
January 2022 in “المجلة العراقية للصيدلة” Minoxidil, a hair growth stimulant, is effective in treating hair loss and new formulas like nanoemulsion and nanocarrier systems have improved its delivery.
May 2026 in “Drug Delivery” Bubble microneedles deliver drugs quickly and effectively through the skin and mouth.
January 2013 in “프로그램북(구 초록집)” Home-use microneedles with 5% minoxidil are safe and effective for hair growth.
April 2026 in “ACS Applied Materials & Interfaces” A new treatment using probiotic microneedles shows promise for promoting hair growth and reducing inflammation in androgenetic alopecia.
1 citations
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January 1981 in “Elsevier eBooks” Melatonin stops melanin production after tyrosinase action, with cyclic GMP mimicking this effect.
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June 2023 in “Chemical engineering journal” A new microneedle patch treats hair loss effectively with fewer side effects and less frequent use.
Solanum nigrum may help treat hair loss.
August 2025 in “Indian Dermatology Online Journal” Combining minoxidil with phototherapy improves vitiligo treatment better than phototherapy alone.
January 2023 in “Theranostics” A patch with curcumin-zinc can improve hair growth and health by delivering beneficial particles to the skin, increasing hair follicles, and reversing effects of a hair loss hormone.
November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Plant-based nanovesicles effectively deliver finasteride for hair regrowth in androgenetic alopecia.
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July 2019 in “Chemical papers/Chemické zvesti” A new sensor can detect minoxidil accurately and effectively.
477 citations
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March 2004 in “Proceedings of the National Academy of Sciences” The DMI3 gene is essential for nodule development and symbiosis in certain plants.
February 2019 in “International Journal of Dermatology and Clinical Research” Nε-(carboxymethyl) lysine delays hair growth by blocking a key protein.
The combination of minoxidil, microneedling, and PRP is more effective for hair growth than minoxidil alone.
April 2023 in “Advances in Natural Sciences: Nanoscience and Nanotechnology” The new formulation with minoxidil, chitosan, and Aloe vera improves hair growth and reduces side effects.
Combining minoxidil with microneedling may be more effective for hair growth than using minoxidil alone.
March 2025 in “Drug Development Research” The new gel combining minoxidil and tofacitinib effectively treats alopecia areata by promoting hair growth and reducing inflammation.
August 2021 in “Josai University Repository of Academia (Josai University)” The nanoparticles improved minoxidil's skin absorption, making them promising for skin treatments.
2 citations
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July 2018 in “Our Dermatology Online” Calcipotriol cream reduced skin thickening and itching in a rare nipple condition.