research Dutasteride reduces alcohol’s sedative effects in men in a human laboratory setting and reduces drinking in the natural environment
Dutasteride makes alcohol less sedating and may lead to less drinking in men.
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research Transdermal film-loaded finasteride microplates to enhance drug skin permeation: Two-step optimization study
Optimized film improves finasteride skin absorption and treatment efficiency.
research Immune modulation of hair follicle regeneration
Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
research Women's midlife health Reframing menopause
The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.
research Hedonic sensitivity to natural rewards is affected by prenatal stress in a sex-dependent manner
Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.
research Micro-segmental hair analysis: detailed procedures and applications in forensic toxicology
Micro-segmental hair analysis helps detect drug use patterns and estimate drug consumption days.
research Whole Genome Scan and Selection Signatures for Climate Adaption in Yanbian Cattle
The CORT, FGF5, and CD36 genes are crucial for the cold weather adaptation of Yanbian cattle.
research Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology
Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.
research Complications in Hair Restoration Surgery
Successful hair transplant surgery depends on careful patient selection, proper surgical plan and technique, and attentive aftercare.
research Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research Frontal Fibrosing Alopecia: A Review
Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
research Human pollution exposure correlates with accelerated ultrastructural degradation of hair fibers
Pollution exposure speeds up hair damage.
research Aromatic plants as cosmeceuticals: benefits and applications for skin health
Aromatic plants can naturally help prevent skin aging and improve skin health.
research Skin transcriptome profiling of Changthangi goats highlights the relevance of genes involved in Pashmina production
Changthangi goats have specific genes that help produce Pashmina wool.
research Dehydroepiandrosterone for women in the peri- or postmenopausal phase
DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
research Effects of finasteride, a 5 alpha-reductase inhibitor, on circulating androgens and gonadotropin secretion in hirsute women.
Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
research Mechanisms underlying select chemotherapeutic-agent-induced neuroinflammation and subsequent neurodegeneration
Chemotherapy can cause brain inflammation and damage, and understanding this process could help manage side effects.
research Vesicles: Potential nano carriers for the delivery of skin cosmetics
Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.
research Interventions for female pattern hair loss
Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.
research Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage
Honokiol helps protect skin from damage and aging caused by cigarette smoke.
research Effect of Ultraviolet Radiation, Smoking and Nutrition on Hair
Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
research A Holistic Approach to Antiaging as an Adjunct to Antiaging Procedures: A Review of the Literature
Combining cosmetic procedures with lifestyle changes improves antiaging results.
research Novel Anti-Melanogenesis Properties of Polydeoxyribonucleotide, a Popular Wound Healing Booster
Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.
research Rabson-Mendenhall syndrome: two case reports and a brief review of the literature
The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.
research Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry
Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.
research Apocrine sweat gland obstruction by antiperspirants allowing transdermal absorption of cutaneous generated hormones and pheromones as a link to the observed incidence rates of breast and prostate cancer in the 20th century
The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
research Analysis of lncRNAs Expression Profiles in Hair Follicle of Hu Sheep Lambskin
lncRNAs may regulate hair follicle development in Hu sheep.
research Metabolic study of androsta-1,4,6-triene-3,17-dione in horses using liquid chromatography/high resolution mass spectrometry
The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.
research Neonatal finasteride administration alters hippocampal α4 and δ GABAAR subunits expression and behavioural responses to progesterone in adult rats
research Commentary: Unroofing for hidradenitis suppurativa, why and how
Unroofing is an effective, less invasive, and cost-effective surgery for hidradenitis suppurativa with low recurrence and improved patient quality of life.