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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Dutasteride works better than finasteride for hair growth with similar side effects.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Low-dose methotrexate, combined with surgical and local treatments, effectively treats severe vulvovaginal lichen planus.

Testosterone's muscle-building effects do not require its conversion to DHT.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.

Telitacicept effectively improved hair regrowth in a woman with lupus and alopecia.

Cyclosporin A, a drug, reduces TGF-β2 expression in skin cells, potentially causing excessive hair growth through a process involving the calcineurin/NFAT pathway.

Higher testosterone and DHT levels are not linked to urinary symptoms in men.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Intralesional steroids effectively treated a young female's scalp nodules without recurrence.

The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

Tofacitinib is more effective than methotrexate for treating moderate-to-severe alopecia areata.

Finasteride can help with hair loss and prostate issues but may negatively affect mood and the nervous system.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by blocking male sex hormones.

Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.

New drugs face challenges due to limited evidence, and safety updates are advised for some existing medications.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Some prostate cancers have gene changes that may affect treatment with certain drugs.

A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.

Finasteride effectively treated hidradenitis suppurativa.

Acne not improved by usual treatments may indicate a genetic disorder.

Combining pulsed prednisone with tofacitinib can lead to lasting hair regrowth in severe alopecia areata patients.