35 citations
,
October 2004 in “Biology of Reproduction” PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
83 citations
,
December 2001 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
5 citations
,
August 2018 in “Sexual Medicine Reviews” 5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
6 citations
,
January 2016 in “Journal of Clinical and Diagnostic Research” Topical minoxidil might potentially cause vision problems, but more research is needed.
33 citations
,
May 2013 in “Andrologia” Some herbs show promise as antiandrogenic agents.
February 2024 in “The Journal of Sexual Medicine” 5-α reductase inhibitors do not significantly affect male reproductive function but may reduce semen volume.
26 citations
,
May 2012 in “Pharmaceutical Development and Technology” PEVs effectively deliver minoxidil through skin.
October 2025 in “Transplantation” Dissolving microneedles with finasteride improve drug delivery for hair loss treatment.
December 2025 in “Molecules” DPP may help hair regrowth by improving blood vessel function under stress.
May 2026 in “International Journal of Drug Delivery Technology” Nanotechnology improves the effectiveness of medicinal plant compounds in drug delivery.
8 citations
,
October 2024 in “Cochrane Database of Systematic Reviews” Tolvaptan can slow kidney disease progression, but doesn't affect mortality or kidney failure.
February 2024 in “The journal of sexual medicine” Flibanserin shows promise for treating male sexual dysfunction but has side effects like insomnia and fatigue.
45 citations
,
July 2025 in “Journal of Medicinal Chemistry” Vepdegestrant may become the first FDA-approved PROTAC degrader, marking a new era in drug development.
12 citations
,
June 2001 in “Bioorganic & Medicinal Chemistry” Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
16 citations
,
October 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Dutasteride may protect the brain in early Parkinson's disease.
November 2021 in “Zenodo (CERN European Organization for Nuclear Research)” Nanosuspension increased finasteride's water solubility by over 2.5 times.
3 citations
,
January 1988 Minoxidil helps hair grow, especially in people with mild hair loss.
3 citations
,
September 2020 in “Bladder cancer” 5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.
January 2003 in “Zhonghua shiyan waike zazhi” Androgen increases VEGF expression but not VEGFR-2 in rat corpus cavernous.
22 citations
,
August 1999 in “Experimental Dermatology” Certain drugs can cause early hair growth in mice by affecting the nerves.
January 2013 in “Journal of Chengdu Medical College” Tolterodine Tartrate effectively treats overactive bladder symptoms.
90 citations
,
January 2003 in “The Journal of Urology” Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.
42 citations
,
August 2012 in “Psychoneuroendocrinology” Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.
8 citations
,
June 1995 in “Helvetica Chimica Acta” Compound 15a was effective in inhibiting 5α-reductase.
December 2010 in “Journal of the American Geriatrics Society” Older adults on certain medications should be carefully monitored for urinary issues and low sodium levels.
26 citations
,
July 2014 in “Analytical Chemistry Research” Method can accurately measure five BPH drugs at once.
2152 citations
,
November 2013 in “Urologia Internationalis” Many men under 40 with erectile dysfunction have organic causes like vascular issues, medication side effects, or hormonal problems.
397 citations
,
February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
April 2026 in “Journal of the American Academy of Dermatology” Oral 5-alpha-reductase inhibitors for hair loss don't increase heart risk.
September 2012 in “DOAJ (DOAJ: Directory of Open Access Journals)” D-004 shows moderate antidepressant effects but is less effective than Sertraline and Imipramine.