150 citations
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April 1999 in “Dermatologic Clinics” Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.
149 citations
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June 2002 in “Veterinary record/The veterinary record” Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.
143 citations
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January 2013 in “Dermatologic surgery” In-office laser hair removal works well long-term, especially Nd:YAG for darker skin, but home devices need more testing.
135 citations
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August 1994 in “Clinical Endocrinology” Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.
130 citations
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January 2017 in “International journal of nanomedicine” Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
109 citations
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March 2011 in “Journal of controlled release” New micelle solutions greatly improve skin delivery of certain antifungal drugs.
108 citations
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December 2003 in “Lasers in surgery and medicine” ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.
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August 1998 in “Pain” Blocking GABA(A) receptors increases neuron sensitivity, showing GABA and glycine have different roles in pain.
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November 2014 in “International Journal of Nanomedicine” Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
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November 2006 in “European Journal of Neuroscience” Progesterone protects rat brain cells by enhancing GABA A receptor activity.
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July 2011 in “Lasers in Medical Science” The Lexington LaserComb helped regrow hair in mice with a condition similar to human hair loss.
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November 2001 in “European journal of endocrinology” Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.
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December 1998 in “Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology” The study improved understanding of keratin fiber structure by showing consistent microfibril diameter but varying distances and electron density profiles.
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October 2010 in “Journal of biomedical nanotechnology” Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
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May 2014 in “International journal of pharmaceutics” Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.
57 citations
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December 2011 in “Lasers in Surgery and Medicine” Selective photothermolysis can target sebaceous glands and may treat acne effectively.
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February 1994 in “Experimental dermatology” Melatonin affects mouse skin and may regulate skin functions.
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March 2017 in “Plant and Cell Physiology” Light sheet fluorescence microscopy effectively measures calcium changes in Arabidopsis root hairs.
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May 2007 in “Australasian journal of dermatology” Two boys developed a viral skin infection during chemotherapy, which resolved with improved immune function.
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March 2009 in “Die Pharmazie” Minoxidil-loaded nanostructured lipid carriers are effective for topical use.
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January 2016 in “Journal of Nanomaterials” Silver nanoparticles from Ziziphus nummularia leaves have better antibacterial, antifungal, antioxidant, and hair growth effects than the leaf extract alone.
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September 2017 in “Lasers in Surgery and Medicine” LED light therapy may help hair growth by activating certain cell pathways.
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January 2009 in “Colloids and Surfaces B: Biointerfaces” A certain surfactant sticks to human hair, making it change from water-repelling to water-attracting, which could help in hair conditioning.
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March 2017 in “PLoS neglected tropical diseases” Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.
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July 2001 in “PubMed” Estrogens can reduce DHT production in hair follicles, but are less effective than finasteride and progesterone.
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January 2013 in “Skin pharmacology and physiology” Nanoparticles show promise for drug delivery through hair follicles but not through healthy skin.
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April 2012 in “Journal of controlled release” New method uses hair follicles to deliver drugs deep into the skin.
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October 2014 in “Langmuir” Bleaching hair removes its protective top layer and exposes more hydrophilic groups, changing its chemical surface and affecting how it interacts with products.
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October 2015 in “International Journal of Pharmaceutics” Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.
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May 2013 in “Andrologia” Some herbs show promise as antiandrogenic agents.