research Witnessed trauma exposure induces fear in mice through a reduction in endogenous neurosteroid synthesis
Reduced neurosteroid production increases fear in mice, suggesting potential PTSD treatments.
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research Ocular Effects of Cosmetic Products and Procedures
Cosmetics and procedures can cause eye issues, from mild discomfort to serious conditions, due to allergies, toxins, or poor care.
research Inhibition of the pro-oxidant effects of benoxaprofen on poiymorpbonuclear leucocytes by retinol acetate in vitro
Retinol acetate can reduce the harmful effects of the drug benoxaprofen on white blood cells.
research NIEFARMAKOLOGICZNA METODA REDUKCJI BÓLU FIZYCZNEGO POPRZEZ ZMIANĘ RODZAJU UWAGI. OPIS PRZYPADKÓW I METODY
Shifting attention can reduce physical pain.
research Signal Mining for Non-Bleeding Adverse Event in Novel Oral Anticoagulants: A Pharmacovigilance Study Based on the FAERS Database
Different oral anticoagulants cause various non-bleeding side effects, so careful monitoring is needed.
research Anti-anginal and beta-adrenoceptor blocking drugs
Beta-blockers and anti-anginal medications have various side effects and interactions that require careful monitoring and individualized treatment.
research Early postnatal allopregnanolone levels alteration and adult behavioral disruption in rats: Implication for drug abuse
Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.
research Nucleus‐specific modulation of phasic and tonic inhibition by endogenous neurosteroidogenesis in the murine thalamus
Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.
research Post-Drug Syndromes: A Neglected Challenge in Pharmacovigilance and Public Health
Current drug safety systems fail to detect long-term side effects, leading to preventable health issues.
research The effect of night shift work on the expression of clock genes in beard hair follicle cells
Night shift work disrupts the body's natural clock genes.
research Relating neurosteroid modulation of inhibitory neurotransmission to behaviour
Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
research Temporary Facial Blanching After Botulinum Toxin Injection in Asian: A Case Report and Review of the Literature
Temporary facial blanching can occur after Botulinum toxin injections, but it resolves without discomfort.
research Greater Placebo Effect in Topical Than in Systemic Therapies for Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Topical hair loss treatments have a stronger placebo effect than systemic ones.
research The Effects of Induced Polycystic Ovary Syndrome in NAG-1 Transgenic Mice
NAG-1 may help prevent some metabolic issues related to PCOS.
research Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats
A neurosteroid can reduce caffeine-induced anxiety in rats.
research Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation
Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
research Molecular insights into chronotype and time-of-day effects on decision-making
People's decision-making can be influenced by their internal biological clocks, as shown by gene expression, not just self-reported preferences for morning or evening.
research Prescribers alerted to potential adverse effects of finasteride and montelukast
research Designing a Placebo Microneedle Stamp: Modeling and Validation in a Clinical Control Trial
The placebo microneedle stamp didn't penetrate skin and caused less pain, but blinding was only effective for those with low skin sensitivity.
research Bilateral nevus comedonicus: efficacy of topical tacalcitol ointment
Tacalcitol ointment effectively improves bilateral nevus comedonicus.
research Greater Placebo Effect in Topical Than in Systemic Therapies for Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Topical treatments for hair loss have a stronger placebo effect than systemic ones.
research The Opiate Antagonist, Naltrexone, in the Treatment of Trichotillomania
Naltrexone did not significantly reduce hair pulling but improved cognitive flexibility.
research Results in a ‘Flash’: Recognizing Misleading Clinical Photography
Be critical of before-and-after photos in dermatology to avoid misleading impressions.
research Alteration of neonatal Allopregnanolone levels affects exploration, anxiety, aversive learning and adult behavioural response to intrahippocampal neurosteroids
Changing Allopregnanolone levels in newborns affects adult behavior and anxiety.
research Drug related lipid metabolism abnormalities: a real-world pharmacovigilance exploratory analysis based on U.S. FDA adverse event reporting system (FAERS)
Many drugs can cause lipid metabolism issues, and labels need better warnings.
research Hormesis and medicine
Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
research The potential involvement of cholinergic system in finasteride induced cognitive dysfunction
Finasteride might affect memory by impacting cholinergic system.
research Effects of Restraint Stress and Allopregnanolone Inhibition on Amphetamine Locomotor Sensitivity
Targeting neurosteroids may help prevent drug relapse.
research Allopregnanolone and Induction of Endogenous Opioid Inhibition of Oxytocin Responses to Immune Stress in Pregnant Rats
Allopregnanolone helps control oxytocin levels during pregnancy to prevent preterm labor.
research Unconventional side effects of antidepressants: Focus on emotional blunting
Some antidepressants can cause emotional numbness and other unusual side effects.