1 citations
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September 2025 in “Physiologia” Ovalbumin–aluminum sensitization causes increased pain sensitivity and nerve changes in mice.
94 citations
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January 2016 in “Journal of the European Academy of Dermatology and Venereology” Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” HSD11b1 affects skin nerves and increases non-histaminergic itch.
76 citations
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March 2005 in “Journal of Molecular Medicine” Certain mice without specific receptors or mast cells don't lose hair from stress.
101 citations
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January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” Nerves and chemicals in the body can affect hair growth and loss.
April 2022 in “Journal of The American Academy of Dermatology” The document suggests that nerve issues might contribute to hair loss and that testing sensation could predict these nerve problems.
27 citations
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August 2003 in “Anais Brasileiros de Dermatologia” Neuropeptides affect skin inflammation, repair, and hair growth, with potential for therapy.
7 citations
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July 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Human skin can be reconnected to nerves using stem cells, which may help with skin health and healing.
1 citations
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April 2022 in “Journal of The American Academy of Dermatology” Hair loss in men (androgenetic alopecia) is significantly linked to decreased scalp sensitivity, but not temperature sensitivity. More research is needed to confirm this. Comparing this hair loss to leprosy is unsupported and stigmatizing.
6 citations
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December 2019 in “BMC Complementary and Alternative Medicine” Alcohol extract from Vernonia anthelmintica seeds may help treat stress-related hair loss.
January 2012 in “Methods in pharmacology and toxicology” TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.
71 citations
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February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
115 citations
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October 2003 in “Journal of Neuroscience” Aβ afferents do not sprout into the superficial spinal cord layers after nerve injury.
11 citations
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September 2011 in “Biochemical journal” Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
286 citations
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April 2009 in “The journal of neuroscience/The Journal of neuroscience” TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.
28 citations
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March 2017 in “Scientific Reports” Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.
September 2017 in “Plastic and Reconstructive Surgery – Global Open” Some migraine sufferers had no more headaches after getting a hair transplant.
31 citations
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November 2016 in “Cell Reports” Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
Iron deficiency anemia can cause itching, which often improves with iron supplements.
March 2024 in “International journal of molecular sciences” taVNS reduces vitiligo symptoms in mice.
260 citations
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January 2020 in “Nature” Stress can cause hair to turn gray by depleting stem cells.
6 citations
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September 2023 in “Experimental physiology” A special receptor in sensory nerve endings helps control how they respond to stretching.
August 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.
2 citations
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June 2025 in “International Journal of Nanomedicine” New biomaterials can improve wound healing by promoting nerve and tissue regeneration.
CRPS I is complex, linked to immune and nerve issues, and needs comprehensive treatment.
57 citations
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March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
123 citations
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November 2003 in “Neuroscience Letters” TRPV4 helps sense pressure in mouse skin.
140 citations
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February 2014 in “Neuron” Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.
426 citations
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August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
1 citations
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October 2022 in “Annual review of cell and developmental biology” The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.