research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
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research Generating detailed intercellular communication patterns in psoriasis at the single-cell level using social networking, pattern recognition, and manifold learning methods to optimize treatment strategies
New insights into cell communication in psoriasis suggest innovative drug treatments.
research Transgenic mice display hair loss and regrowth overexpressing mutant <i>Hr</i> gene
Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.
research The agouti mouse model: an epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome
Diet changes can protect against harmful environmental effects on fetal development.
research ATP-dependent chromatin remodeling during mammalian development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research Androgen receptor: A promising therapeutic target in breast cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
research CD201+ fascia progenitors choreograph injury repair
CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.
research In-silico cardiac aging regulatory model including microRNA post-transcriptional regulation
Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.
research MendelVar: gene prioritization at GWAS loci using phenotypic enrichment of Mendelian disease genes
MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.
research Roles of steroid sulfatase in brain and other tissues
Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
research Progesterone, neurosteroids, and the hormonal basis of catamenial epilepsy
Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
research <p>DNA phenotyping: current application in forensic science</p>
DNA phenotyping helps predict physical traits from DNA with varying accuracy and requires careful ethical and legal handling.
research New substrates for stem cell control
New materials help control stem cell growth and specialization for medical applications.
research Neurotrophin-4 modulates the mechanotransducer Cav3.2 T-type calcium current in mice down-hair neurons
Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
research Controversies in plastic surgery: Suction-assisted lipectomy (SAL) and the hCG (human chorionic gonadotropin) protocol for obesity treatment
The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.
research Treating psychogenic nonepileptic seizures: Easier said than done
Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.
research Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis
Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
research Besnoitiosis in donkeys: an emerging parasitic disease of equids in Italy
Besnoitiosis, a parasitic disease, has been found in donkeys in Italy and may be more common in Europe than previously thought.
research Implications of neuroimaging for the treatment of epilepsy
Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.
research Provocating factors of vitiligo
Stress can trigger and worsen vitiligo.
research The Molecular Pathogenesis of Trichilemmal Carcinoma
Trichilemmal carcinoma shares genetic traits with other skin cancers, suggesting similar treatment options.
research The Molecular Pathogenesis of Trichilemmal Carcinoma
Trichilemmal carcinoma shares genetic traits with other skin cancers, suggesting similar treatment options.
research Characterization of a Partial cDNA for Lysyl Hydroxylase from Human Skin Fibroblasts; Lysyl Hydroxylase mRNAs Are Regulated Differently by Minoxidil Derivatives and Hydralazine
Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.
research MicroRNA/mRNA regulatory networks in the control of skin development and regeneration
MicroRNAs are crucial for controlling skin development and healing by regulating genes.
research MicroRNA in skin diseases
Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
research Defining microRNA signatures of hair follicular stem and progenitor cells in healthy and androgenic alopecia patients
Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
research Predisposing and Overall Effects of Reproductive Hormones on Breast Cancer: A Review
Reproductive hormones play a crucial role in breast cancer development and treatment challenges.
research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin
The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
research Differential expression analysis of balding and nonbalding dermal papilla microRNAs in male pattern baldness with a microRNA amplification profiling method
Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.
research Analysis of histological and microRNA profiles changes in rabbit skin development
Rabbit skin analysis showed changes in hair growth and identified miRNAs that may regulate hair follicle development.