65 citations
,
May 2006 in “Journal of Investigative Dermatology” Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.
14 citations
,
September 2017 in “Hormones and behavior” δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.
24 citations
,
October 2012 in “The International Journal of Biochemistry & Cell Biology” Testosterone protects female heart cells from stress by activating estrogen receptors.
22 citations
,
January 2001 in “Chemical & Pharmaceutical Bulletin” Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
28 citations
,
August 2000 in “Current Opinion in Chemical Biology” Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.
431 citations
,
October 2008 in “Current Medicinal Chemistry” Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
January 1994 in “European Journal of Cancer” The European School of Oncology organized various educational events in 1994, highlighting important cancer research findings.
22 citations
,
March 2018 in “International Ophthalmology” Taking tamsulosin or finasteride and being older increase the risk of floppy iris during cataract surgery.
4 citations
,
August 2021 in “Biomedicine & Pharmacotherapy” 5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.
1 citations
,
January 2014 in “Side effects of drugs annual” Hormonal contraceptives and related compounds can increase health risks like thrombosis and affect sexual function.
April 2026 in “Cosmetics” The formulation significantly increased hair density and thickness safely in people with androgenetic alopecia.
7 citations
,
September 2023 in “Cancer Treatment Reviews” Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.
18 citations
,
July 2015 in “Drug Healthcare and Patient Safety” Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.
8 citations
,
December 2022 in “Nature Reviews Endocrinology” Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.
51 citations
,
April 1999 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
19 citations
,
September 2013 in “Psychoneuroendocrinology” Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.
8 citations
,
May 2025 in “Pharmaceuticals” In 2024, the FDA approved 27 innovative small-molecule drugs, with many offering significant treatment improvements.
26 citations
,
March 2018 in “Experimental Dermatology” Prolactin may influence skin glands and could be a target for treating acne and skin aging.
September 2025 in “Healthcare” SSRIs may help manage sexual behavior in dementia patients, but they can cause long-lasting sexual dysfunction.
13 citations
,
August 2007 in “Bioorganic & medicinal chemistry letters” A new compound effectively inhibits human 5α-reductase 1.
48 citations
,
January 2000 in “Hormone Research in Paediatrics” Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
4 citations
,
August 2010 in “Acta Biologica Hungarica” New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.
25 citations
,
May 2003 in “Expert Opinion on Therapeutic Patents” Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” Steroid-producing capabilities in certain cancers may contribute to treatment resistance.
61 citations
,
April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
60 citations
,
November 2009 in “General and Comparative Endocrinology” Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
9 citations
,
March 1991 in “Endocrinology” Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
72 citations
,
January 2011 in “Current Pharmaceutical Design” S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
51 citations
,
May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Certain drugs that block specific enzymes can help treat prostate diseases.
20 citations
,
January 2019 in “Journal of dermatological science” Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.