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Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.

Overexpression of IKZF1 and Ikaros causes hair loss in mice similar to alopecia areata.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

Mutations in certain receptors can cause diseases and offer new treatment options.

Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

New compounds show promise as nonsteroidal treatments for hair loss.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

Finasteride may improve prostate cancer treatment outcomes.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

New treatments for male hypogonadism are effective and should be personalized.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.