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A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

The guideline emphasizes a multidisciplinary approach and informed consent for gender-affirming hormone treatment, with regular follow-ups and individualized care.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Gender-affirming hormone therapy in South Korea aligns with international guidelines and has specific side effects.

Gender-affirming hormone therapy affects metabolism differently based on treatment type.

Masculinizing hormone therapy increases the risk of hair loss in transgender and gender-diverse patients.

Provide individualized, supportive care for transgender and non-binary adolescents to improve their well-being.

More research is needed to improve lower body gender affirmation techniques.

Social rejection can harm long-term mental health in transgender individuals.

Transgender individuals face unique skin issues, often due to hormone therapy, requiring specialized and stigma-free dermatologic care.

A new gene mutation causes complete androgen insensitivity in a 16-year-old with a female appearance.

Younger transgender women have surgery earlier, are mostly attracted to men, and show more preoperative depression that improves after surgery compared to older transgender women.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Diagnosing osteoporosis in transgender people is challenging due to unclear guidelines and hormone treatment effects.

Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.

Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.

Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.

Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Many children and teens referred to gender services receive hormone treatments, but more research is needed on their long-term care and outcomes.

The patient had complex urinary tract issues and ambiguous genitalia, with physical features suggesting a hormonal imbalance.

Transgender women have similar fitness to cisgender women, while transgender men have higher fat and lower strength than cisgender men; hormone therapy affects body composition and strength.

Polycystic Ovary Syndrome (PCOS) affects Iranian women's feelings of femininity and self-image.

Facial hair is crucial for transgender men's gender identity and transition.

Hormonal treatments can change hair and skin in transgender people, but may not fully achieve desired results.

Hair transplantation is important for transgender patients to enhance their masculine or feminine appearance.

Australia needs better dermatological guidelines for gender-diverse patients.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Eating disorders in gender dysphoria patients may be a coping mechanism for body image issues.