research Comprehensive clinical management of hirsutism
New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.
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150-180 / 1000+ results research Differences in the mechanisms of androgen action in hair follicles from women and men with androgenetic alopecia
research Progress on the mechanism of natural products alleviating androgenetic alopecia
Natural products might be safe, effective, and affordable treatments for hair loss.
research Pathogenic Mechanisms and Mechanism‐Directed Therapies for Androgenetic Alopecia: Current Understanding and Future Directions
Targeting multiple pathways may improve treatments for androgenetic alopecia.
research New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway
New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
research Discovery of Nonsteroidal Androgens
Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.
research ANTIANDROGENS AND THE SKIN
Antiandrogens can treat acne, hirsutism, and seborrhea by reducing sebum production and androgen action.
research Biochemical Mechanisms Regulating Human Hair Growth
Androgens shorten hair growth phases, causing finer hair and more severe hair loss in men.
research BIOLOGICAL ACTIVITY OF ANTIANDROGENS
Antiandrogens may help treat conditions like excessive hair growth, prostate tumors, male baldness, and acne by blocking male hormone effects.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research Silencing the androgen receptor: New skills for antiandrogen oligonucleotide skin and hair therapy
Targeting androgen receptors with antiandrogen oligonucleotides could effectively treat hair loss.
research Do androgens really play a major role in the pathophysiology of androgenetic alopecia?
Androgens might not be the only major factor in hair loss; other elements could also be important.
research Progestogens with Antiandrogenic Properties
research The effects of synthetic 19-norprogestins on osteoblastic cell function are mediated by their non-phenolic reduced metabolites
Synthetic 19-norprogestins promote bone cell growth and function through their non-phenolic metabolites.
research Mechanisms of testosterone action
Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.
research Immune and Non-immune Interactions in the Pathogenesis of Androgenetic Alopecia
research Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia
Androgens prevent hair growth by changing Wnt signals in cells.
research Androgen antagonists in androgen target tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes
Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.
research Molecular Basis of Androgenetic Alopecia
research Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia
Androgens may block hair growth signals, targeting this could treat hair loss.
research 1407 ANDROGENETIC ALOPECIA, PROSTATE VOLUME AND URINARY SYMPTOMS. IS THERE A RELATIONSHIP? A CASE-CONTROL STUDY
Hair loss, prostate size, and urinary issues are related due to androgen effects.
research Molecular interactions of progesterone derivatives with 5α-reductase types 1 and 2 and androgen receptors
Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.
research Hormonal regulation in male androgenetic alopecia—Sex hormones and beyond: Evidence from recent genetic studies
Hormones and genes affect hair growth and male baldness.
research The mechanism of inheritance of androgenetic alopecias in women
research Topical Antiandrogens
Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.
research Evaluation of New Pregnane Derivatives as 5.ALPHA.-Reductase Inhibitor.
New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
research Mechanism of action of bolandiol (19-nortestosterone-3β,17β-diol), a unique anabolic steroid with androgenic, estrogenic, and progestational activities
Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
research Mechanotransduction in Androgenetic Alopecia: An In Silico Repositioning Study of PIEZO1 + MLCK Axis Using Cofolding and Pilosebaceous Single-Cell Atlas Constraints
Potential compounds may inhibit hair loss by targeting a non-androgen pathway.