4 citations
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January 2018 in “General Physiology and Biophysics” The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.
3 citations
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June 2015 in “Serbian Journal of Dermatology and Venereology” The conclusion is that cerebrovascular diseases can cause seizure-like activity in stroke patients, which can be improved with antiepileptic drugs.
8 citations
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February 2003 in “Annals of Neurology” Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.
February 2009 in “Mayo Clinic proceedings” A woman's new seizures were caused by a brain tumor likely linked to her past cancer treatment, and choosing safe seizure medications is important for women who can have children.
May 2024 in “Brain disorders” Agmatine may help reduce seizures linked to hormone changes in female rats.
30 citations
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February 2003 in “Annals of Neurology” Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
23 citations
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July 2003 in “Pharmacology, Biochemistry and Behavior” Finasteride blocks progesterone's effect on absence seizures in rats.
May 2025 in “Neuropharmacology” Finasteride reduced seizures and prevented cognitive issues in rats after neonatal asphyxia but increased anxiety later.
2 citations
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February 2003 in “Annals of Neurology” Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.
20 citations
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January 2017 in “Epilepsia” Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.
65 citations
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October 2008 in “Journal of Neuroendocrinology” Convulsofin effectively treats primary epilepsy but has some side effects.
January 2008 in “Elsevier eBooks” The young woman with epilepsy became seizure-free after finding the right combination of medications.
170 citations
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June 1974 in “BMJ” Sodium valproate effectively reduces seizures in epilepsy, especially in absences and myoclonic types, with minimal side effects.
44 citations
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December 1975 in “Developmental Medicine & Child Neurology” Sodium valproate effectively controls petit mal seizures in children but is less effective for other types, with minimal side effects.
24 citations
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November 1978 in “JAMA” Valproic acid is effective for various seizures, but may cause temporary side effects like drowsiness and stomach issues.
1 citations
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December 1982 in “PubMed” Sodium valproate effectively reduces seizures in children with epilepsy, especially in primary generalized cases.
24 citations
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January 2007 in “The FASEB Journal” Neurosteroid withdrawal increases seizure frequency in a rat model of catamenial epilepsy.
2 citations
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November 1978 in “JAMA” Valproic acid is an effective seizure medication with some temporary side effects.
12 citations
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February 2017 in “Journal of neuroscience research” Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.
Levetiracetam and valproate sodium both reduce seizures when added to lamotrigine, but levetiracetam has fewer side effects.
294 citations
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February 1994 in “PubMed” Valproic acid is an effective and safe first-choice treatment for many types of seizures.
5 citations
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January 2017 in “Nevrologiâ, nejropsihiatriâ, psihosomatika” Sustained-release sodium valproate is effective in treating epilepsy, with some side effects influenced by genetics.
60 citations
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December 2013 in “PLoS ONE” EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.
10 citations
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October 2016 in “Epilepsy & behavior” Levetiracetam often causes behavioral issues, while oxcarbazepine is more likely to cause sleepiness in epilepsy patients.
59 citations
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October 1976 in “Acta Neurologica Scandinavica” Sodium valproate reduced seizures in many patients with resistant epilepsy.
55 citations
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December 1983 in “Acta Neurologica Scandinavica” Carbamazepine, valproate, and clonazepam can cause mild to serious side effects during long-term epilepsy treatment.
May 2022 in “Indian Journal of Pharmacology” Sodium valproate can cause serious high blood pressure in children.
January 2017 in “Elsevier eBooks” Stress and hormones like progesterone can affect absence seizures, but their effects change with different life stages.
17 citations
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October 1980 in “PubMed” Valproic acid is effective for controlling seizures in children, especially as a single treatment, with some side effects.