835 citations
,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
February 2016 in “Science” Foxc1 and COL17A1 are crucial for maintaining healthy hair follicles and preventing hair loss.
17 citations
,
April 2017 in “PLoS ONE” Hair follicle cells can become bone-like cells, useful for bone repair.
36 citations
,
April 2016 in “Biochimie” A substance called epidermal growth factor helps increase the growth of important hair follicle cells by activating a specific cell communication route.
January 2008 in “Chinese bulletin of Life sciences” Epidermal stem cells help renew skin and regenerate hair follicles.
21 citations
,
March 2019 in “Experimental Dermatology” Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
11 citations
,
August 1987 in “Archives of Dermatology” Langerhans' cells are not involved in hair depigmentation in these mice.
April 2017 in “Plastic and reconstructive surgery. Global open” Baby and adult skin cells are different, with baby cells having more active pathways that could help grow new hair follicles.
71 citations
,
January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
13 citations
,
January 2002 in “Biochemical and biophysical research communications” Interferon β from hair cells stops the growth of other hair cells.
22 citations
,
December 1991 in “PubMed”
205 citations
,
April 2005 in “Journal of Investigative Dermatology” Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
January 2003 in “Zhonghua shaoshang zazhi” Murine fetal epidermal stem cells can help regenerate hair follicles.
111 citations
,
April 2000 in “British journal of dermatology/British journal of dermatology, Supplement” Thyroid hormone receptor β1 is found in human hair follicles and helps them survive.
16 citations
,
November 2020 in “In Vitro Cellular & Developmental Biology - Animal” Microfollicles can effectively model human hair follicles for research and testing.
February 2026 in “International Journal of Molecular Sciences” Removing Lrig1-positive cells in mice leads to temporary loss of sebaceous glands.
August 1994 in “Journal of dermatological science” Different substances affect hair and skin cell growth in various ways, with some promoting and others inhibiting cell proliferation.
3 citations
,
December 2024 in “Journal of Animal Physiology and Animal Nutrition” FGF20 is essential for hair follicle stem cell growth and development in fine-wool sheep.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Human hair follicles can be used to create heart muscle cells.
45 citations
,
May 2022 in “Biomedicines” Analyzing follicular fluid can help predict and improve outcomes for women with PCOS undergoing fertility treatments.
1 citations
,
January 2020 in “Microscopy research” Researchers successfully grew hair follicle stem cells from mice and humans, which could be useful for tissue engineering and regenerative medicine.
1 citations
,
July 2025 in “Scientific Reports” CD133+ cells are crucial for hair growth.
43 citations
,
December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
8 citations
,
September 2024 in “BMC Genomics” circCFAP20DC helps goat ovarian cells grow, aiding follicle development.
24 citations
,
September 2002 in “Dermatologic Surgery” The study found that hair follicles are above muscle connections in the scalp, which may help protect stem cell areas.
15 citations
,
July 2017 in “PubMed” Injecting a mix of human skin and hair cells into mice can grow new hair.
March 2026 in “Dermatology Online Journal” Cystic panfolliculoma is a rare, harmless tumor that can be confused with other skin tumors.
January 2022 in “Stem cell biology and regenerative medicine” Dermal sheath cells can help grow new hair follicles and show promise in treating hair loss.
December 2015 in “Vascular Pharmacology” Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.
46 citations
,
November 2014 in “Journal of Cutaneous Pathology” Recognizing diverse presentations of folliculotropic mycosis fungoides is crucial to avoid diagnostic errors.