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Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

Keratinocytes can reduce the survival of certain melanoma cells, suggesting new therapy paths.

GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.

Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

The SLICK1 allele in Holstein heifers affects hair and immune traits without altering prolactin signaling.

Sex hormones may be linked to inflammation in Hidradenitis Suppurativa.

Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

17-beta estradiol and prednisolone may help regrow hair damaged by chemotherapy.

Allopregnanolone likely doesn't influence ethanol's rewarding effects in these mice.

Anabolic steroids may help prevent aging effects by reducing toxicity, not by their usual functions.

Cyclooxygenase-2 overexpression in mice skin causes hair loss like human androgenetic alopecia.

Human adrenals and gonads have a unique enzyme for steroid hormone production.

Blocking TGFβ can help treat fibrotic skin conditions by promoting fat cell formation.

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

Injecting steroids like Triamcinolone Acetonide for skin treatments can cause Cushing's Syndrome.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

Lack of vitamin D receptor causes hair loss in mice by allowing certain genes to overactivate.

Progesterone protects neurons from damage by converting to allopregnanolone, which works through GABAA receptors.

Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.

Targeting NCoR1 can help treat heart enlargement and dysfunction.

The HCR gene contributes to psoriasis risk.

Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.

Notch signaling is essential for healthy skin and hair follicle maintenance.

MC-1R is present in skin cells and may help reduce inflammation.

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

Blocking BMP signaling causes hair loss and disrupts hair growth cycles.