Plakophilin 1 helps control skin cell immune responses to prevent excessive inflammation.
11 citations
,
April 2022 in “Biophysical Journal” Disulfide bonds in keratin fibers break more easily under stress, especially when wet, affecting fiber strength.
15 citations
,
January 1987 in “Electrophoresis” Human head hair proteins can be typed into eight distinct patterns, useful for genetic and forensic investigations.
16 citations
,
September 2018 in “Scientific reports” Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
45 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Adhesion molecules are crucial for the development of feathers and hair.
Transglutaminases help form strong hair by linking proteins, and can potentially alter hair properties.
28 citations
,
July 1980 in “British Journal of Dermatology” The hair disorder was caused by abnormal protein formation, making hair easily damaged.
107 citations
,
October 2014 in “PeerJ” Hair's molecular structure is mostly consistent, but genetic differences affect lipid types, which could help diagnose diseases.
2 citations
,
November 2019 in “Cancer reports” The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
1 citations
,
January 2006 High temperatures and cosmetic processes can damage hair keratin, affecting its structure and strength.
21 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Most mouse hair keratin genes are on chromosomes 11 and 15.
January 2016 in “Frontiers in Bioengineering and Biotechnology” A wool hair keratin hydrogel is promising for growing cells and tissue engineering.
5 citations
,
May 2023 in “Microbial Cell Factories” A stable, active version of a growth factor was made in bacteria, showing promise for medical use.
3 citations
,
September 2023 in “Genes” Dkk genes evolved faster in birds and reptiles, affecting hair development functions.
Epimorphin helps shape and develop epithelial cells, like those in hair follicles.
143 citations
,
January 2012 in “Cell and Tissue Research”
November 2023 in “Advanced Science” A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
6 citations
,
February 2013 in “British Journal of Dermatology” Androgens significantly regulate hair keratin K37 expression.
39 citations
,
November 2007 in “Journal of Histochemistry & Cytochemistry” NG2 is crucial for normal skin and hair development in mice.
29 citations
,
July 2003 in “Experimental Dermatology” The upper hair follicle is stable, while the lower part allows movement during hair growth.
8 citations
,
June 2016 in “Journal of Investigative Dermatology” A rare genetic deletion in the KRT1 gene causes unique skin symptoms in a family.
October 2015 in “Cosmetic Dermatology” Hair is complex, varies in type, and plays a big role in attractiveness and culture.
8 citations
,
May 2005 in “The American journal of dermatopathology/American journal of dermatopathology” The hair defect is due to abnormal inner root sheath keratinization.
NuMA-microtubule interactions are vital for proper skin structure formation and function.
79 citations
,
August 1998 in “The Journal of Cell Biology” Keratin 16 delays skin maturation and affects skin and hair development in mice.
January 2006 in “Carl von Ossiezky University of Oldenburg” Unpigmented keratinocytes absorb substances faster, while melanocytes bind more strongly to melanin.
January 2012 in “eScholarship (California Digital Library)” Hair and nails contain stable RNA, useful for personalized medicine and screening.
70 citations
,
December 1968 in “Journal of Investigative Dermatology” 10 citations
,
January 2001 in “PubMed” Laminin, type IV collagen, and fibronectin help develop skin and hair structures in embryos.
26 citations
,
January 2011 in “Open Journal of Genetics” The KAP13-3 gene in sheep affects wool quality by influencing keratin assembly.